Dasatinib

Dosage Forms Available

• Dasatinib can be taken orally (tablet).

Age and Dose Restrictions

• This medicine is meant for adults and children aged 1 year and older.

Contraindications

• This medicine is contraindicated in patients with known hypersensitivity to Dasatinib. It should be used cautiously in patients with a history of heart problems, risk factors for pulmonary hypertension, a history of bleeding or liver problems, or long QT syndrome.

Other Medications to Avoid

• Dasatinib can interact with strong Antacids (e.g., aluminium hydroxide, magnesium hydroxide).

Overdose and Missed Dose

• An overdose of Dasatinib primarily results in severe myelosuppression that causes fatigue, increased infection risk, easy bruising, bleeding, and shortness of breath. If you observe this symptom, inform your doctor immediately.

• If you forget to take this medicine, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If you experience fluid retention, reduce your salt intake.

• To manage nausea and vomiting, try taking Dasatinib with food.

• If you experience diarrhoea, drink plenty of water to stay hydrated.

Use in Driving and Operating Machinery

• Dasatinib may affect your ability to drive or operate heavy machinery due to its potential side effects such as dizziness and fatigue. If you feel dizzy after taking this medication, avoid driving or operating heavy machinery until these symptoms pass.

Use in Pregnancy and Lactation

• Dasatinib should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. Breastfeeding is not recommended during treatment with this medicine.

Caution in Other Conditions

• Patients with kidney or liver impairment do not require dosage adjustments when taking Dasatinib. However, caution should be exercised when administering this medication to these patients due to the potential risk of increased side effects.

Special Dietary and Lifestyle Recommendations

• Make sure to drink plenty of fluids to stay hydrated, especially if you experience diarrhoea or vomiting.

• Practise good hygiene to reduce your risk of infection while taking Dasatinib.