Degarelix

Dosage Forms Available

• Degarelix is available in the form of a powder that is meant for reconstitution (injection).

Age and Dose Restrictions

• This medication is meant for adult males, specifically those diagnosed with advanced prostate cancer.

Contraindications

• Degarelix is contraindicated in patients with known hypersensitivity to the medicine or any of its components. It should be used with caution in patients with a history of long QT syndrome or cardiovascular disease.

Other Medications to Avoid

• Degarelix can interact with medicines that may prolong the QT interval, such as certain antiarrhythmics (like amiodarone and sotalol), antipsychotics (like haloperidol and chlorpromazine), and antibiotics (like ciprofloxacin and erythromycin).

Overdose and Missed Dose

• Overdose of Degarelix may result in symptoms such as nausea, vomiting, increased heart rate, or changes in blood pressure. If you experience any of these symptoms, contact your doctor immediately.

• If you miss a dose of this medicine, inform your doctor promptly. Your doctor will determine when the next dose should be given to maintain consistent testosterone suppression.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage injection site reactions, apply a cold compress to the area after administration.

• Hot flashes can be managed by avoiding triggers like caffeine and spicy foods.

• Regular rest and maintaining hydration can help manage fatigue.

Use in Driving and Operating Machinery

• There is no known effect of Degarelix on the ability to drive or operate machinery. However, if you feel dizzy or unwell after administration, avoid these activities until you feel better.

Use in Pregnancy and Lactation

• Degarelix is not meant for use in women.

Caution in Other Conditions

• Patients with electrolyte abnormalities should exercise caution when taking Degarelix as it may prolong the QT interval.

• Those with heart conditions should use Degarelix carefully, as it may influence heart function and blood pressure.

• Patients with osteoporosis should be cautious, as Degarelix may impact bone density over time.

Special Dietary and Lifestyle Recommendations

• Frequent hydration is recommended as hormone therapy can sometimes cause feelings of dryness or dehydration.

• Ensure adequate intake of calcium and vitamin D to support bone health, as Degarelix may impact bone density over time.

• Regularly check electrolyte levels, as Degarelix can affect these and potentially prolong the QT interval.