Desidustat

Expert Advice

Dosage Forms Available

• Desidustat is available in the form of oral tablets.

• This allows it to be taken through the mouth.

Age and Dose Restrictions

• Desidustat is meant for adult use, specifically for those diagnosed with chronic kidney disease (CKD).

Contraindications

• Desidustat is contraindicated in patients with a history of cardiovascular disease.

• It is also contraindicated for those who have suffered from stroke or thrombosis.

Other Medications to Avoid

• Desidustat can interact with anticoagulants (such as warfarin, dabigatran), antiplatelet agents (such as aspirin, clopidogrel), and medications affecting liver enzymes (such as ketoconazole, rifampin). It may also interact with blood pressure-lowering medications (such as amlodipine, lisinopril), erythropoiesis-stimulating agents (such as darbepoetin alfa, epoetin alfa), and iron supplements (such as ferrous sulfate, ferric carboxymaltose).

• Careful monitoring and consulting a healthcare provider are essential when taking other medications with Desidustat.

Overdose and Missed Dose

• An overdose of Desidustat may lead to complications such as an increased risk of blood clots or severe hypertension. If you suspect an overdose, it is crucial to seek immediate medical attention.

• If you miss a dose of Desidustat, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of the symptoms, please consult your doctor.

• To manage nausea, try taking Desidustat with food or a glass of water.

• If experiencing headaches, resting in a quiet, dark room may help alleviate the discomfort.

Use in Driving and Operating Machinery

• Desidustat may cause dizziness or fatigue. It is advisable to avoid driving or operating heavy machinery if you experience these symptoms after taking the medication.

Use in Pregnancy and Lactation

• The safety of Desidustat during pregnancy and lactation has not been established. It should only be used if the potential benefits justify the potential risks to the foetus or infant.

• Always consult your doctor before using Desidustat during pregnancy or while breastfeeding.

Caution in Other Conditions

• Caution is advised when administering Desidustat to patients with renal impairment as dose adjustment may be necessary.

• Patients with hepatic conditions should also be closely monitored due to the potential impact on medicinal metabolism.

Special Dietary and Lifestyle Recommendations

• Maintain adequate hydration by drinking plenty of water throughout the day, which can help manage potential side effects like headaches and nausea.

• A balanced diet rich in iron and vitamins may aid in managing anaemia associated with CKD.

• Avoid high-potassium foods such as bananas and potatoes if you are at risk of hyperkalemia—a side effect noted with Desidustat usage.

• Regular monitoring of blood pressure and kidney function tests are recommended while managing CKD with medications like Desidustat.

• Engage in light to moderate physical activities, such as walking or swimming, which can improve overall well-being without excessive strain on the kidneys.

Frequently asked questions

Terms & Conditions