Desloratadine + Montelukast
Uses of Desloratadine + Montelukast
Desloratadine + Montelukast is primarily used to manage symptoms associated with seasonal allergic rhinitis (hay fever) and belongs to a group of medications known as antihistamines and leukotriene receptor antagonists respectively.
It is also useful in managing urticaria (skin allergy), sneezing, runny nose, itchy nose, itchy eyes, nasal congestion, and difficulty breathing.
Side effects of Desloratadine + Montelukast
Headache
Fatigue
Drowsiness
Dry mouth
Nausea
How Desloratadine + Montelukast works
Desloratadine belongs to the antihistamines class of medicines. It works by selectively blocking histamine H1 receptors. Histamine is a chemical in the body that triggers allergic reactions. By inhibiting these receptors, Desloratadine reduces the effects of histamine, providing relief from symptoms such as sneezing, runny nose, and itchy or watery eyes.
Montelukast is a leukotriene receptor antagonist. It works by blocking a substance called leukotriene D4 from attaching to its receptor in the lungs and airways. This helps to reduce inflammation, prevent the airways from narrowing, and decrease mucus production. As a result, Montelukast effectively relieves both nasal and bronchial symptoms of allergic rhinitis (hay fever).
Certified content
Written By
BDS, MDS
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
Desloratadine + Montelukast is available in tablet form for oral administration.
Age and Dose Restrictions
This medicine is meant for adults and adolescents above 15 years of age.
Contraindications
Desloratadine + Montelukast is contraindicated in patients with known hypersensitivity to desloratadine, loratadine, montelukast, or any of the other ingredients in the formulation.
It is also contraindicated in patients with severe liver impairment and severe kidney impairment.
Other Medications to Avoid
This medicine can interact with macrolide antibiotics (such as erythromycin), antifungals (such as ketoconazole), CYP3A4 inducers (such as phenytoin or rifampin), antihistamines (such as diphenhydramine) and CNS depressants (such as diazepam).
Overdose and Missed Dose
An overdose of Desloratadine + Montelukast may cause severe drowsiness. In such a case, seek immediate medical attention.
If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not take two doses at once.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Nonetheless, if you experience any side effects, try taking the medicine with food or at bedtime.
Drinking plenty of water may also help to alleviate dry mouth.
Use in Driving and Operating Machinery
Desloratadine + Montelukast can cause drowsiness and dizziness. If you experience these side effects, avoid driving or operating heavy machinery.
Use in Pregnancy and Lactation
Consult your doctor before using this medicine during pregnancy or if you are breastfeeding.
Caution in Other Conditions
Patients with a history of mental health disorders should use Desloratadine + Montelukast with caution.
Elderly patients should also use it cautiously as they may have reduced kidney function.
Special Dietary and Lifestyle Recommendations
Avoid potential allergens, such as dust and pollen, as much as possible.
Keep windows closed during high pollen seasons.
Wash your hands frequently to decrease the chance of contaminating your eyes or nose with allergens.
Use air purifiers to reduce indoor allergens.
Frequently asked questions
Can Desloratadine + Montelukast affect my mood or behaviour?
Desloratadine + Montelukast can affect behaviour or mood. If you notice any unusual mood or behaviour changes while taking this medication, seek immediate medical attention.
Can Desloratadine + Montelukast affect sleep?
Desloratadine + Montelukast may cause sleepiness or somnolence. If this happens, you should consult your doctor.
Is Desloratadine + Montelukast a steroid?
No, Desloratadine + Montelukast is not a steroid. It is a combination of an antihistamine (Desloratadine) and a leukotriene receptor antagonist (Montelukast).
Is Desloratadine + Montelukast safe for long-term use?
Yes, Desloratadine + Montelukast can be taken for long-term use. However, it should be taken only as per the doctor's prescription and direction.
How soon can I expect relief after taking Desloratadine + Montelukast?
Some relief from allergy symptoms may be observed within an hour of taking Desloratadine + Montelukast. However, the maximum effectiveness may take several days of regular dosing.
Will Desloratadine + Montelukast have any impact on fertility?
Desloratadine + Montelukast is not directly associated with affecting fertility. However, if you have concerns about fertility, it would be best to consult with your doctor.
Can I buy Desloratadine + Montelukast without a prescription?
No, Desloratadine + Montelukast is not available over the counter. It requires a prescription from a doctor.
Desloratadine + Montelukast in other salts
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