Dexamethasone + Tobramycin
Uses of Dexamethasone + Tobramycin
Dexamethasone + Tobramycin is primarily used to manage bacterial eye infections, which are associated with inflammation. It belongs to a group of medicines known as corticosteroids and antibiotics.
Aside from this, the combination can also be used to prevent eye inflammation and infection after certain eye surgeries, such as cataract removal.
Side effects of Dexamethasone + Tobramycin
Temporary blurred vision
Eye redness, irritation, burning, itching, or stinging
Increased eye sensitivity
Mild headaches
How Dexamethasone + Tobramycin works
Dexamethasone + Tobramycin belongs to the category of ophthalmic medications used to treat eye infections and associated inflammation.
Dexamethasone is a corticosteroid. It functions by binding to specific receptors in the body, thereby triggering a reaction that decreases inflammation. This is achieved by suppressing substances that cause inflammation, such as cytokines and prostaglandins, leading to a reduction in swelling, redness, and pain.
Tobramycin is an aminoglycoside antibiotic. It works by adhering to specific parts of bacteria, disrupting their ability to create proteins, which they need to grow and multiply. This disruption eventually leads to the death of the bacteria, helping manage the infection.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage forms available
Dexamethasone + Tobramycin is available in topical forms such as eye drops and ointments.
These formulations are applied directly to the affected eyes.
Age and dose restrictions
The use of Dexamethasone + Tobramycin is generally intended for adults and children who are old enough to be able to follow the instructions for use.
Specific age restrictions may vary based on the condition being managed and individual patient factors.
Contraindications
Dexamethasone + Tobramycin is contraindicated in patients with known hypersensitivity to either Dexamethasone or Tobramycin.
It should not be used in cases of viral, fungal, or mycobacterial eye infections.
It is also contraindicated in suspected or confirmed cases of increased ocular pressure or glaucoma.
Other medications to avoid with this medicine
Dexamethasone + Tobramycin may interact with several medications, including other corticosteroid eye drops (such as prednisolone), antibiotic eye drops (like ciprofloxacin), and intraocular pressure-lowering agents (such as timolol).
Overdose and missed dose
Overdose from topical use of Dexamethasone + Tobramycin is highly unlikely. However, if accidentally ingested, supportive care should be provided. Hemodialysis may be necessary to remove Tobramycin from the blood.
If you miss a dose, apply it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and resume your usual dosing schedule.
Management of side effects
Most side effects of Dexamethasone + Tobramycin are temporary and resolve once the medication is discontinued. If severe side effects occur or symptoms worsen, consult your doctor.
Rest your eyes for a few minutes after applying the drops and avoid activities like driving until your vision clears.
Wear sunglasses to protect your eyes from bright light or glare when outdoors.
Use in driving and operating machinery
Dexamethasone + Tobramycin does not usually affect the ability to drive or operate machinery. However, if you experience blurred vision or other eye-related issues, avoid these activities until your vision clears.
Use in pregnancy and lactation
Dexamethasone + Tobramycin is classified as pregnancy category C. It should only be used during pregnancy if the potential benefit outweighs the potential risk.
It is unknown whether topical Dexamethasone or Tobramycin enters breast milk. A decision should be made to either discontinue nursing or discontinue the medication which will be advised by your doctor.
Caution in other conditions
Caution should be exercised in patients with diabetes as corticosteroids like Dexamethasone may increase blood glucose levels.
Caution is also advised for patients prone to developing cataracts, as corticosteroids may speed up cataract formation.
Patients with compromised corneal integrity should use this medication with caution due to the risk of delayed healing.
Special dietary and lifestyle recommendation
Maintain good hygiene to avoid worsening of infections being managed by Dexamethasone + Tobramycin.
For eye infections, avoid touching or rubbing your eyes and use clean towels and bed linens.
Frequently asked questions
Is Dexamethasone + Tobramycin a steroid?
Yes, Dexamethasone in Dexamethasone + Tobramycin combination is a type of corticosteroid. It works by reducing inflammation in your body. Tobramycin, on the other hand, is an antibiotic that fights bacteria.
How quickly does Dexamethasone + Tobramycin work?
Dexamethasone + Tobramycin begins working soon after you apply it, but the duration before you start seeing improvement varies from person to person and condition to condition. Significant improvement is usually observed within a few days to a week of consistent use.
Can Dexamethasone + Tobramycin be used for ear infections?
Dexamethasone + Tobramycin is typically used for eye infections. However, your doctor may prescribe it for other conditions if they believe it will be beneficial. Always use this medication as directed by your doctor.
Can I use Dexamethasone + Tobramycin for longer than prescribed if my symptoms persist?
No, you should not use Dexamethasone + Tobramycin longer than your doctor prescribes, even if your symptoms persist. Overuse can lead to complications like antibiotic resistance and fungal overgrowth.
Does Dexamethasone + Tobramycin have any effect on sleep?
Dexamethasone + Tobramycin is not known to directly affect sleep. Since it is used locally in the eye, systemic absorption is minimal, so sleep disturbances are uncommon. However, if you experience any unusual side effects, consult your doctor.
Will Dexamethasone + Tobramycin affect my mood or appetite?
There is no concrete evidence to suggest that Dexamethasone + Tobramycin has a significant impact on mood or appetite.
Is Dexamethasone + Tobramycin available over the counter, or do I need a prescription?
Dexamethasone + Tobramycin usually requires a prescription and is not typically available over the counter.
Dexamethasone + Tobramycin in other salts
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