Dexketoprofen + Paracetamol/acetaminophen

Dosage Forms Available

• Dexketoprofen + Paracetamol/Acetaminophen is available as oral tablets and powders.

• In addition, this combination also available in effervescent tablets or suspension forms for ease of administration, particularly for patients who have difficulty swallowing tablets.

Age and Dose Restrictions

• This medicine is meant for use in adult patients only.

Contraindications

• This combination is contraindicated in patients with hypersensitivity to any of its components.

• It is also contraindicated in people with active peptic ulcer, gastrointestinal bleeding, inflammatory bowel disease, severe heart failure, and severe renal or hepatic insufficiency.

• Patients who have experienced asthma or bronchospasm related to NSAIDs usage should not use this combination.

Other Medications to Avoid

• This combination may interact with other NSAIDs (such as ibuprofen and aspirin), diuretics (like furosemide), antihypertensives (such as lisinopril), anticoagulants (like warfarin), SSRIs (such as fluoxetine), cardiac glycosides (including digoxin), cyclosporine, and medications that affect liver enzymes such as CYP2E1 inducers (like rifampicin).

Overdose and Missed Dose

• An overdose of this combination may result in gastrointestinal symptoms, drowsiness, dizziness, hypotension, renal failure, and respiratory depression. In case of suspected overdose, seek immediate medical attention.

• If you miss a dose of this combination, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the forgotten one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage mild gastrointestinal upset, consider taking the medication with food or a glass of milk.

• Ensure adequate hydration by drinking plenty of water throughout the day which may help alleviate some side effects like dizziness or headache.

Use in Driving and Operating Machinery

• Dexketoprofen + Paracetamol/Acetaminophen may cause dizziness or drowsiness. Therefore, avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

• Dexketoprofen + Paracetamol/Acetaminophen is contraindicated in the third trimester of pregnancy and is not recommended during the first and second trimesters unless clearly necessary. The combination should be avoided during breastfeeding.

• Consult your doctor before using this medicine during pregnancy and lactation.

Caution in Other Conditions

• Caution is advised when using this medication in the elderly or those with renal or hepatic impairment.

• Individuals with hypertension or cardiac conditions should also use this medication cautiously.

Special Dietary and Lifestyle Recommendations

• Stay hydrated by drinking plenty of water which can aid in maintaining good kidney function while on this medication.

• Avoid excessive intake of salt to manage blood pressure levels if you are prone to hypertension.