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Diethylcarbamazine

ANTHELMINTIC

Uses of Diethylcarbamazine

  • Diethylcarbamazine is an antiparasitic medicine. It is used for the treatment of certain filarial infections like infestation by Wuchereria bancrofti, Brugia malayi, Brugia timori, infestation by Loa loa and infestation with Onchocerca volvulus.

Side effects of Diethylcarbamazine

  • Fever
  • Headaches
  • Dizziness
  • Loss of appetite
  • Hives
  • Vomiting
  • Asthma attack

How Diethylcarbamazine works

  • This medication acts by releasing the excretory antigen from microfilariae, killing the free radicals, drug-induced changes in metabolism in the microfilariae and/or host endothelial cells, which is triggered by platelets and results in immobilisation of microfilariae on endothelial surfaces and inhibits microtubule polymerization.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • This medicine can be taken orally (tablet and syrup).

Age and Dose Restrictions

  • This medicine should be taken with the dosage and duration as advised by the doctor.

Contraindications

  • It is contraindicated in patients with a history of hypersensitivity to Diethylcarbamazine, in patients with serious eye damage and in patients with a gluten intolerance, as this medicine contains gluten.

Other Medications To Avoid With This Medicine

  • Avoid taking cholinergic medications (acetylcholine, atropine), potassium channel blockers (amifampridine), tricyclic antidepressants (amitryptiline), and beta-blockers (atenolol). These medications may alter the safety and effectiveness of this medication.

Overdose and Missed Dose

  • Consult your doctor if you experience any severe side effects or worsening of any of the symptoms in case of overdosage. Strict adherence to the prescribed dose is essential.
  • If you miss a dose of this medicine, take it as soon as you remember, but if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • Take this medicine with food to reduce gastrointestinal side effects and continue taking it as prescribed. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This medicine can cause drowsiness as a side effect. It’s advised to refrain from driving or operating machinery after taking this medicine.

Use in Pregnancy and Lactation

  • This medicine is not recommended to be used in pregnancy and while breastfeeding.

Caution in Other Conditions

  • Caution is advised in older adults and patients with galactosemia, glucose or galactose malabsorption syndrome or lactase deficiency and gluten intolerance.
  • Dosage adjustment is required in case of patients with kidney disorders.

Special Dietary & Lifestyle Recommendation

  • Include foods with antiparasitic properties in your diet. Such foods include raw garlic, pumpkin seeds, pomegranates, beets and carrots.
  • Reduce sugar intake as it promotes the growth and division of the parasites.
  • Take a balanced diet to nourish the body and the brain. 
  • Avoid consumption of alcohol and usage of tobacco.

Frequently asked questions

Dosage adjustment is required for this medicine in the case of elderly patients with kidney disease. 

Yes, this medicine can potentially interact with medications such as cholinergic medications, potassium channel blockers, tricyclic antidepressants, and beta blockers.

No, this medicine is not recommended for use during pregnancy.  

No, this medicine is not recommended for use while breastfeeding.

Terms & Conditions


Available medicines for DIETHYLCARBAMAZINE
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