Diloxanide + Tinidazole

Dosage Forms Available

• Diloxanide + Tinidazole is available in oral form as tablets.

Age and Dose Restrictions

• This combination is generally prescribed to adults and children above 10 years of age.

• Dosage recommendations vary based on the type and severity of the infection. It’s important to adhere strictly to the dosage prescribed by your doctor, as it will be tailored to your individual needs. Adjustments might be required for those with liver or kidney impairments.

Contraindications

• Diloxanide + Tinidazole is contraindicated in individuals with a known hypersensitivity to either Diloxanide, Tinidazole or other nitroimidazole derivatives.

• It should not be used in individuals with blood dyscrasias or severe hepatic impairment.

Other Medications to Avoid

• The combination of Diloxanide + Tinidazole may interact with anticoagulants (such as warfarin, heparin), chemotherapy medications (like fluorouracil, cisplatin), immunosuppressants (such as cyclosporine, tacrolimus), mood stabilisers (like lithium, carbamazepine), and gastrointestinal medications (such as cimetidine, ranitidine).

Overdose and Missed Dose

• Overdosing can intensify side effects like nausea, vomiting, ataxia, and paresthesias. If you observe these symptoms, seek medical attention immediately.

• In case you miss a dose, take it as soon as possible. However, if it's almost time for the next dose, skip the missed one and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage nausea and vomiting, try taking this medicine with food.

• If you experience dizziness or fatigue, avoid sudden changes in position to prevent falling.

Use in Driving and Operating Machinery

• Dizziness and fatigue are potential side effects of this combination. Therefore, it is advisable not to drive or operate heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

• Diloxanide + Tinidazole should be used during pregnancy only if needed, especially during the first trimester. Both medicines are excreted in breast milk - breastfeeding should be avoided during treatment. Always consult your doctor before starting any medication during pregnancy or lactation.

Caution in Other Conditions

• People with liver problems should use this combination with caution as the medicine is metabolised in the liver.

• Also, it may prolong the QT interval; people with heart conditions that might be affected by this should use it with caution.

Special Dietary and Lifestyle Recommendations

• Maintain good personal hygiene to prevent re-infection with intestinal parasites.

• Wash fruits and vegetables thoroughly before consumption.