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Domperidone + Lafutidine

Uses of Domperidone + Lafutidine

  • Domperidone + Lafutidine is primarily used to manage various gastrointestinal disorders including gastroesophageal reflux disease (GERD) and peptic ulcers. It belongs to the class of gastroprotective and prokinetic medications.

  • Secondary uses of Domperidone + Lafutidine include managing non-ulcer dyspepsia and relieving symptoms like stomach pain, bloating, and feeling of fullness. It is also used as an add-on treatment for the eradication of Helicobacter pylori (H. pylori) bacteria.

Side effects of Domperidone + Lafutidine

  • Headache

  • Dizziness

  • Dry mouth

  • Diarrhoea

  • Abdominal pain

How Domperidone + Lafutidine works

  • Domperidone is a dopamine-2 receptor antagonist. It increases the contractions of the stomach and its emptying speed. It also prevents feelings of nausea and vomiting by blocking dopamine receptors in the brain.

  • Lafutidine is an H2-receptor antagonist. It limits the production of stomach acid by blocking histamine's action on cells in the stomach lining. Additionally, it supports the gastric mucosa, the stomach's protective layer, by increasing mucus secretion and enhancing blood flow.

  • When working together, Domperidone and Lafutidine help minimise acid reflux, speed up ulcer healing, and provide respite from unpleasant gastrointestinal symptoms.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Domperidone + Lafutidine is available for oral administration in two forms: tablet and capsule.

Age and Dose Restrictions

  • This medicine is meant for use in adults over 18 years of age.

Contraindications

  • This medicine is contraindicated in patients with known hypersensitivity to Domperidone or Lafutidine.

  • It is also contraindicated in patients with prolactinoma, pituitary tumours, gastrointestinal perforation or obstruction, and moderate to severe liver impairment.

Other Medications to Avoid

  • Domperidone + Lafutidine may interact with antacids and proton pump inhibitors (such as omeprazole and lansoprazole), strong CYP3A4 inhibitors (like ketoconazole, itraconazole), QT-prolonging medicines (such as quinidine, amiodarone), anticholinergic medicines (like hyoscine, atropine) and cardiac glycosides (like digoxin).

Overdose and Missed Dose

  • An overdose of Domperidone + Lafutidine may lead to symptoms such as confusion, disorientation and difficulty in walking and speaking. If you suspect an overdose, consult your doctor immediately.

  • If you forget to take a dose of this medicine, take it as soon as you remember. However, if it’s almost time for the next dose, skip the missed dose and take the next one at the regular time. Do not double the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Staying hydrated can help manage side effects like dry mouth and constipation.

  • Taking this medicine with food can help reduce side effects such as abdominal pain and diarrhoea.

  • Rest techniques can help manage side effects like headaches and dizziness.

Use in Driving and Operating Machinery

  • Domperidone + Lafutidine may cause dizziness or drowsiness. If you experience these symptoms, avoid driving or operating heavy machinery until you feel alert again.

Use in Pregnancy and Lactation

  • Consult your doctor before using Domperidone + Lafutidine during pregnancy and breastfeeding.

Caution in Other Conditions

  • Patients with kidney disease or liver impairment should exercise caution when taking Domperidone + Lafutidine. Regular monitoring of kidney function and liver function may be required during treatment with this medicine.

Special Dietary and Lifestyle Recommendations

  • A diet low in spicy, acidic, and fatty foods can help manage symptoms of gastroesophageal reflux disease (GERD) and peptic ulcers.

  • Regular moderate-intensity exercise can improve digestion and reduce stress, both of which can help manage gastrointestinal disorders.

Frequently asked questions

No, Domperidone + Lafutidine is not a steroid. It is a combination of two active medicinal ingredients domperidone, a dopamine-2 receptor antagonist, and lafutidine, an H2-receptor antagonist. The combination is primarily used to manage various gastrointestinal disorders.

Domperidone + Lafutidine does not typically cause sleep disturbances. However, individuals can experience different reactions to medicines, and if you experience any unusual effects on your sleep, consult your doctor.

Domperidone + Lafutidine is not associated with having an impact on an individual's fertility. If you have concerns about this issue, it is advisable to discuss them with your doctor.

Domperidone + Lafutidine can be taken daily if prescribed by your doctor for managing certain medical conditions like GERD and peptic ulcers.

The time it takes for Domperidone + Lafutidine to work can vary depending on the individual and the condition being managed. Your doctor will be able to provide more specific information based on your situation.

Domperidone + Lafutidine is typically recommended to be taken before meals. However, the best time to take this medicine can vary depending on your specific condition and how your body responds to medication. Your doctor will guide you on the optimal time to take this medicine.

No, Domperidone + Lafutidine is not known to cause dependency or habit formation. It should be taken exactly as prescribed by your doctor.

Terms & Conditions


Available medicines for DOMPERIDONE + LAFUTIDINE
Futaden D 10/30 MG Tablet 10
Futaden D 10/30 MG Tablet 10
Emcure Pharmaceuticals Ltd
Pack of 10 Units
₹81.18
MRP ₹99.00
18.00% OFF
Lafutax D 10/30 MG Capsule 10
Lafutax D 10/30 MG Capsule 10
Ajanta Pharma Ltd
Pack of 10 Units
₹63.14
MRP ₹77.00
18.00% OFF
Lafty D 10/30 MG Capsule 10
Lafty D 10/30 MG Capsule 10
Akumentis Healthcare Ltd
Pack of 10 Units
₹61.50
MRP ₹75.00
18.00% OFF
Lafaxid D Tablet 10
Lafaxid D Tablet 10
Zuventus Healthcare Ltd
Pack of 10 UNITS
₹104.84
MRP ₹127.85
18.00% OFF
Lafumac Dsr 10/30 MG Tablet 10
Lafumac Dsr 10/30 MG Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹62.40
MRP ₹76.10
18.00% OFF
Laciloc D 10/10 MG Capsule 10
Laciloc D 10/10 MG Capsule 10
Cadila Pharmaceuticals Ltd
Pack of 10 Units
₹73.11
MRP ₹89.16
18.00% OFF
Lafudac D 10/30 MG Capsule 10
Lafudac D 10/30 MG Capsule 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹79.75
MRP ₹97.25
18.00% OFF
Lafukem D 10/30 MG Capsule 10
Lafukem D 10/30 MG Capsule 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹56.03
MRP ₹68.33
18.00% OFF

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