Dothiepin / Dosulepin is primarily used to manage major depressive disorder (MDD) and falls under the category of tricyclic antidepressants (TCAs).
Secondary uses of this medicine include managing various anxiety disorders such as generalized anxiety disorder (GAD) and panic disorder and treating certain types of nerve pain like fibromyalgia and neuropathic pain.
Dry mouth, constipation, and increased appetite
Headache, nausea, vomiting
Sweating
Dothiepin / Dosulepin is a Tricyclic Antidepressant (TCA). It operates by inhibiting the reuptake of serotonin and norepinephrine in the brain. This is a simple way of saying it prevents these mood-regulating chemicals from being reabsorbed too quickly into the nerve cells.
Doctor of Medicine
BMS, FMC, MD Resident
Dothiepin / Dosulepin can be taken orally (tablets, capsules).
Dothiepin / Dosulepin is meant for use in adults.
Dothiepin / Dosulepin is contraindicated in patients with known allergy to any of its ingredients. This medicine is also contraindicated for individuals who have recently had a heart attack or have severe liver disease.
Dothiepin / Dosulepin can interact with monoamine oxidase inhibitors (MAOIs) (such as phenelzine and selegiline), other antidepressants (like fluoxetine and sertraline) and anticholinergic medications (such as atropine and scopolamine).
An overdose of Dothiepin / Dosulepin may cause drowsiness, confusion, seizures, irregular heart rhythms, or difficulty breathing. If you suspect an overdose, seek immediate medical attention.
If you forget to take your dose of Dothiepin / Dosulepin, take it as soon as you remember. However, if it is almost time for your next dose, skip the forgotten one and resume your regular dosing schedule. Never double up on doses to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For dry mouth, chewing sugar-free gum or sucking on sugar-free sweets may help.
If you feel dizzy or lightheaded, avoid rapid standing from a sitting or lying position.
Dothiepin / Dosulepin may cause drowsiness, dizziness or blurred vision. Therefore, it can affect your ability to drive or operate machinery. If you feel affected, you should not drive or use machinery.
Dothiepin / Dosulepin should only be used in pregnancy or while breastfeeding if the potential benefit justifies the potential risk to the baby. Always consult your doctor before using this medication during pregnancy or while breastfeeding.
Patients with a history of seizures, heart conditions or urinary retention should exercise caution when taking Dothiepin / Dosulepin. Regular monitoring by a doctor is advised for these patients while taking this medication.
Ensure regular physical activity as it can help reduce anxiety and improve mood.
Getting plenty of sleep can help manage stress and reduce symptoms of depression.
Frequently asked questions
No, Dothiepin / Dosulepin is not a steroid. It is a tricyclic antidepressant used primarily to manage depression, anxiety disorders, and certain types of nerve pain.
No, it's not safe to stop taking Dothiepin (Dosulepin) abruptly. It should be tapered off gradually under medical supervision to avoid withdrawal symptoms.
Yes, Dothiepin / Dosulepin can cause drowsiness and sedation which might affect sleep patterns. Always consult your doctor if these effects persist or worsen.
Dothiepin (Dosulepin) is not known to significantly affect fertility, but there isn't enough research to completely rule out potential effects. It's best to consult a doctor for personalized advice.
Dothiepin / Dosulepin is generally safe to take daily as long as you strictly follow your doctor's prescription and advice.
The time for Dothiepin / Dosulepin to start showing its effects can vary between individuals and depends on the condition being managed. Always consult your doctor for more precise information.
The best time to take Dothiepin / Dosulepin is usually determined by your doctor based on your medical condition and how well you respond to treatment.
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