Doxylamine + Vitamin B6 (pyridoxine)

Dosage Forms Available

• Doxylamine + Vitamin B6 (Pyridoxine) is available in the form of delayed-release tablets.

• This medication is taken orally.

Age and Dose Restrictions

• This medicine is intended for use by adult women, specifically those who are pregnant.

Contraindications

• Doxylamine + Vitamin B6 (Pyridoxine) is contraindicated in individuals with known hypersensitivity to doxylamine, other ethanolamine-derivative antihistamines, or pyridoxine.

• It is also contraindicated in patients with asthma, increased intraocular pressure, narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder neck obstruction.

Other Medications to Avoid

• This combination may interact with monoamine oxidase inhibitors (such as phenelzine and tranylcypromine), CNS depressants (like alprazolam and zolpidem), and other anticholinergic agents (such as atropine and scopolamine).

• Before starting any new medications, consulting a doctor is essential to avoid adverse interactions.

Overdose and Missed Dose

• An overdose of Doxylamine + Vitamin B6 (Pyridoxine) might lead to increased severity of side effects such as severe drowsiness and anticholinergic effects like dry mouth and enlarged pupils. In such cases, contacting a doctor immediately is crucial.

• If a dose of this medicine is missed, it should be taken as soon as remembered unless it is near the time for the next dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage drowsiness, consider taking the medicine at bedtime to ensure sleep is not disrupted.

• If experiencing mild dizziness, ensure to sit or lie down until the feeling passes.

Use in Driving and Operating Machinery

• This medication can cause drowsiness. You should avoid driving or operating heavy machinery until you have determined how Doxylamine + Vitamin B6 (Pyridoxine) affects your ability to perform these activities safely.

Use in Pregnancy and Lactation

• Doxylamine + Vitamin B6 (Pyridoxine) is specifically approved for use during pregnancy for managing nausea.

• The safety of this medication during breastfeeding has not been conclusively established. Consult your doctor before using this medication if breastfeeding.

Caution in Other Conditions

• Individuals with conditions that affect metabolism or excretion, such as liver or kidney disease, should use Doxylamine + Vitamin B6 (Pyridoxine) with caution.

• Patients with these conditions should discuss their health status with their doctor before beginning treatment.

Special Dietary and Lifestyle Recommendations

• To aid in managing nausea and vomiting during pregnancy, small, frequent meals throughout the day may help.

• Staying hydrated by drinking plenty of fluids can also be beneficial.

• Avoiding spicy and fatty foods might reduce nausea incidents.

• Engaging in light activities such as walking can aid digestion and help manage symptoms.

• Ensure a well-ventilated environment as certain smells can trigger nausea.