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Dulaglutide

Uses of Dulaglutide

  • Dulaglutide is primarily used to manage type 2 diabetes in adults and belongs to the category of glucagon-like peptide-1 (GLP-1) receptor agonists.

  • Additionally, this medication is indicated for reducing the risk of major adverse cardiovascular events, which include heart attack and stroke, in patients who have type 2 diabetes and established cardiovascular disease.

Side effects of Dulaglutide

  • Nausea

  • Vomiting

  • Diarrhoea

  • Abdominal pain

  • Decreased appetite

  • Indigestion

  • Fatigue

How Dulaglutide works

  • Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist.

  • It operates by copying the action of incretin, a natural hormone in the body. This leads to several actions that help manage type 2 diabetes.

  • It encourages the pancreas to release insulin when necessary. Insulin is a hormone that allows sugar in the blood to enter cells, thus lowering blood sugar levels.

  • It suppresses the release of glucagon, a hormone that raises blood sugar levels, especially when they are low.

  • It slows down the emptying of the stomach, which reduces appetite and can lead to weight loss.

  • These combined actions help lower blood sugar levels, make you feel full for longer times, and promote weight loss.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 8 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 3 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Dulaglutide is available as pre-filled, single-use pen or syringe for subcutaneous administration.

Age and Dose Restrictions

  • This medicine is intended solely for adult use.

Contraindications

  • Dulaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2).
  • Dulaglutide is contraindicated in severe gastro-intestinal disease.

Other Medications to Avoid

  • This medicine may interact with oral medications that require rapid gastrointestinal absorption, insulin, and insulin secretagogues (such as sulfonylureas).

Overdose and Missed Dose

  • In cases of overdose, patients might experience severe nausea, vomiting, and hypoglycaemia. Immediate medical care is crucial to manage these symptoms effectively.
  • If a dose is missed and it is within 3 days of the scheduled dose, administer it as soon as possible. If more than 3 days have passed, skip the missed dose and administer the next dose on the scheduled day. Do not administer two doses at once.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea, eat smaller, more frequent meals.
  • Stay hydrated to help alleviate symptoms like dry mouth and fatigue.

Use in Driving and Operating Machinery

  • Dulaglutide does not generally affect the ability to drive or operate machinery. However, caution should be exercised if dizziness occurs.

Use in Pregnancy and Lactation

  • Limited data are available on the use of Dulaglutide in pregnancy or lactation. It is advisable to consult your doctor before using Dulaglutide if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with a history of severe gastrointestinal disease or renal impairment should use Dulaglutide with caution.
  • Monitoring of renal function may be necessary during treatment.

Special Dietary and Lifestyle Recommendations

  • Regular physical activity can help enhance the effectiveness of Dulaglutide in controlling blood sugar.
  • Monitor carbohydrate intake to avoid blood sugar spikes.
  • Drinking plenty of water can aid in managing blood sugar levels and reducing side effects such as dry mouth from Dulaglutide.

Frequently asked questions

No, Dulaglutide is not a steroid. It is a medicine that belongs to the class of glucagon-like peptide-1 (GLP-1) receptor agonists and it is used to manage type 2 diabetes in adults.

Dulaglutide does not typically have an impact on sleep. However, every individual is different and may react differently to medications. If you experience any unusual sleep patterns after starting this medication, consult your doctor.

There is no evidence to suggest that Dulaglutide has an impact on fertility. It is always important to discuss any concerns about fertility or family planning with your doctor while taking any medication.

A healthy diet and regular exercise are always recommended when managing diabetes. No specific diet restrictions have been indicated for Dulaglutide, but it is always advisable to avoid foods high in sugar and unhealthy fats.

Dulaglutide is usually administered once weekly, not daily. The day of the week you administer the injection should stay the same every week. Note that the frequency and dosage will be determined by your doctor.

Dulaglutide begins to lower blood sugar levels within a few days of the first injection, but it may take several weeks to see the full effect.

Your doctor will prescribe you the best times for taking this combination.

Terms & Conditions

List of Medicines for Dulaglutide

Trulicity 0.75mg Pre Filled Pen 0.5ml Pack Of 2 Injections
Trulicity 0.75mg Pre Filled Pen 0.5ml Pack Of 2 Injections
Cipla Ltd.
Pack of 2 UNITS
₹4815.52
MRP ₹5497.8
12.41% OFF
Aplevant 0.75mg Pre Filled Pens Pack Of 2 Injections
Aplevant 0.75mg Pre Filled Pens Pack Of 2 Injections
Lupin Ltd
Pack of 2 Units
₹3998.4
MRP ₹4998
20% OFF

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