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Duloxetine + Pregabalin

Uses of Duloxetine + Pregabalin

  • Duloxetine + Pregabalin is primarily used to manage neuropathic pain conditions and belongs to the group of serotonergic and anticonvulsive medicines.

Side effects of Duloxetine + Pregabalin

  • Nausea

  • Dizziness

  • Fatigue

  • Dry mouth

  • Sweating

How Duloxetine + Pregabalin works

  • Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). It works by amplifying the activity of serotonin and norepinephrine, which are neurotransmitters present in the brain and spinal cord.

  • Pregabalin, an anticonvulsant, works differently. It attaches to calcium channels in the nervous system and regulates the inflow of calcium. Working together, these two medicines effectively manage different types of neuropathic pain.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Duloxetine + Pregabalin is available through the oral route in the form of capsules.

Age and Dose Restrictions

  • This medication is usually meant for adults and adolescents aged 17 and over.

Contraindications

  • The Duloxetine + Pregabalin combination is contraindicated in patients with known hypersensitivity to either of the active ingredients, duloxetine or pregabalin.

Other Medications to Avoid

  • Duloxetine + Pregabalin may interact with MAO inhibitors (such as selegiline and rasagiline) and serotonergic medicines such as triptans (like sumatriptan, rizatriptan) and tricyclic antidepressants (like amitriptyline, nortriptyline).

Overdose and Missed Dose

  • Overdosing on Duloxetine + Pregabalin can lead to severe dizziness, nausea, or seizures. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Management of Side Effects

Most side effects are temporary and resolve when discontinuing this medicine. However, if you experience severe side effects or symptoms worsening, please consult your doctor.

  • Drinking plenty of water can help manage some gastrointestinal side effects like constipation.

Use in Driving and Operating Machinery

  • Duloxetine + Pregabalin may cause drowsiness or dizziness. It is recommended to avoid driving or operating heavy machinery until you know how this combination affects you.

Use in Pregnancy and Lactation

  • It's advised to consult your doctor before using Duloxetine + Pregabalin during pregnancy or while breastfeeding, as potential risks to the baby need to be considered.

Caution in Other Conditions

  • Caution is advised in patients with severe renal (kidney) impairment, as duloxetine is substantially excreted by the kidney.

  • Patients with liver disease should also exercise caution, as duloxetine is extensively metabolised in the liver.

Special Dietary and Lifestyle Recommendations

  • Regular, moderate physical activity can help manage pain conditions for which Duloxetine + Pregabalin is prescribed.

  • Adequate sleep and stress management techniques such as meditation or yoga may also enhance overall health and well-being.

Frequently asked questions

No, Duloxetine + Pregabalin is not a steroid. It is a combination medication that contains an antidepressant (Duloxetine) and a pain reliever (Pregabalin).

Yes, one of the common side effects of Duloxetine + Pregabalin can be drowsiness. This may affect your sleep cycle.

Duloxetine + Pregabalin is not typically associated with changes in fertility. However, if you have specific concerns, it's best to consult a doctor.

Yes, it is safe to take Duloxetine + Pregabalin daily as prescribed by your doctor.

The time taken for Duloxetine + Pregabalin to work can vary depending on the individual and the condition being managed. You should start feeling the effects of the medication within a few weeks.

The best time to take Duloxetine + Pregabalin is as recommended by your doctor.

The duration of treatment with Duloxetine + Pregabalin varies depending on the individual and their medical condition.

Terms & Conditions


Available medicines for DULOXETINE + PREGABALIN
Pregalin D 20/75 MG Capsule 10
Pregalin D 20/75 MG Capsule 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹163.18
MRP ₹199.00
18.00% OFF
Pregeb D 75/20 Capsule 10
Pregeb D 75/20 Capsule 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹179.33
MRP ₹218.70
18.00% OFF
Neurokem D 20/50 MG Capsule Dr 10
Neurokem D 20/50 MG Capsule Dr 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹118.90
MRP ₹145.00
18.00% OFF
Peg D 50/20 MG Capsule 10
Peg D 50/20 MG Capsule 10
Ipca Laboratories Pvt Ltd.
Pack of 10 Units
₹116.44
MRP ₹142.00
18.00% OFF
Pregaba D 75/20 MG Capsule 10
Pregaba D 75/20 MG Capsule 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹163.18
MRP ₹199.00
18.00% OFF
Prixain D 50/20 MG Capsule 10
Prixain D 50/20 MG Capsule 10
Ajanta Pharma Ltd
Pack of 10 Units
₹113.98
MRP ₹139.00
18.00% OFF
Prixain D 75/20 MG Capsule 10
Prixain D 75/20 MG Capsule 10
Ajanta Pharma Ltd
Pack of 10 Units
₹163.18
MRP ₹199.00
18.00% OFF
Pregeb D 75/30 MG Capsule 10
Pregeb D 75/30 MG Capsule 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
₹215.37
MRP ₹262.65
18.00% OFF

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