Duloxetine + Pregabalin

Dosage Forms Available

• Duloxetine + Pregabalin is available through the oral route in the form of capsules.

Age and Dose Restrictions

• This medication is usually meant for adults and adolescents aged 17 and over.

Contraindications

• The Duloxetine + Pregabalin combination is contraindicated in patients with known hypersensitivity to either of the active ingredients, duloxetine or pregabalin.

Other Medications to Avoid

• Duloxetine + Pregabalin may interact with MAO inhibitors (such as selegiline and rasagiline) and serotonergic medicines such as triptans (like sumatriptan, rizatriptan) and tricyclic antidepressants (like amitriptyline, nortriptyline).

Overdose and Missed Dose

• Overdosing on Duloxetine + Pregabalin can lead to severe dizziness, nausea, or seizures. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Management of Side Effects

Most side effects are temporary and resolve when discontinuing this medicine. However, if you experience severe side effects or symptoms worsening, please consult your doctor.

• Drinking plenty of water can help manage some gastrointestinal side effects like constipation.

Use in Driving and Operating Machinery

• Duloxetine + Pregabalin may cause drowsiness or dizziness. It is recommended to avoid driving or operating heavy machinery until you know how this combination affects you.

Use in Pregnancy and Lactation

• It's advised to consult your doctor before using Duloxetine + Pregabalin during pregnancy or while breastfeeding, as potential risks to the baby need to be considered.

Caution in Other Conditions

• Caution is advised in patients with severe renal (kidney) impairment, as duloxetine is substantially excreted by the kidney.

• Patients with liver disease should also exercise caution, as duloxetine is extensively metabolised in the liver.

Special Dietary and Lifestyle Recommendations

• Regular, moderate physical activity can help manage pain conditions for which Duloxetine + Pregabalin is prescribed.

• Adequate sleep and stress management techniques such as meditation or yoga may also enhance overall health and well-being.