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Emtricitabine + Tenofovir Disoproxil Fumarate

Uses of Emtricitabine + Tenofovir Disoproxil Fumarate

  • Emtricitabine + Tenofovir Disoproxil Fumarate is primarily used to manage HIV-1 infections. This combination is part of the antiretroviral medication class and is effective in reducing the viral load in HIV-positive individuals.

  • It is also used for pre-exposure prophylaxis (PrEP) to reduce the risk of sexually acquired HIV-1 infection in adults at high risk.

Side effects of Emtricitabine + Tenofovir Disoproxil Fumarate

  • Headache

  • Dizziness

  • Diarrhoea

  • Nausea

  • Fatigue

How Emtricitabine + Tenofovir Disoproxil Fumarate works

  • Emtricitabine + Tenofovir Disoproxil Fumarate is an antiretroviral combination.

  • Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI). It works by blocking a crucial enzyme (reverse transcriptase) that the HIV-1 virus needs to replicate its genetic material, which stops the virus from multiplying.

  • Tenofovir Disoproxil Fumarate is also an NRTI. Like emtricitabine, it blocks the reverse transcriptase enzyme, preventing HIV-1 from copying its genetic material and thus reducing the virus's ability to multiply.

  • When used together, these two components increase the effectiveness of inhibiting the HIV-1 virus's ability to reproduce, thereby decreasing the amount of HIV-1 in the blood and helping your immune system fight off the infection.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Emtricitabine + Tenofovir Disoproxil Fumarate is available for oral consumption in the form of tablets.

Age and Dose Restrictions

  • This medication is meant for adults and children weighing at least 17 kg.

Contraindications

  • Emtricitabine + Tenofovir Disoproxil Fumarate is contraindicated in patients with known hypersensitivity to any components of the product.

Other Medications to Avoid

  • This combination may interact with other antiretroviral medications (such as didanosine) and medication affecting kidney function, including NSAIDs (such as ibuprofen), aminoglycosides (like gentamicin), and amphotericin B.

  • Always inform your doctor about all medicines you are taking to avoid potential interactions.

Overdose and Missed Dose

  • An overdose of this combination could potentially lead to severe adverse effects. If you suspect an overdose, consult a doctor immediately.

  • In case of a missed dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your normal schedule. Do not take two doses at once.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience diarrhoea or nausea after taking this combination, drinking plenty of water may help manage these side effects.

  • Resting and avoiding strenuous activities can help manage fatigue.

Use in Driving and Operating Machinery

This combination may make you feel dizzy or tired. It is advised to avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

  • Emtricitabine + Tenofovir Disoproxil Fumarate is not recommended for use during pregnancy or while breastfeeding unless the benefits greatly outweigh the risks.

  • Consult your doctor before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Caution in Other Conditions

  • Patients with a history of liver or kidney disease should use this combination with caution. Regular monitoring of liver and kidney function is recommended.

Special Dietary and Lifestyle Recommendations

  • It is essential to avoid risky behaviors, such as unprotected sex or sharing needles, to prevent HIV transmission.

  • Regular medical check-ups are necessary for monitoring health status and HIV progression.

  • It is also important to get the necessary vaccines as recommended by your doctor to prevent other infections.

Frequently asked questions

No, this combination is specifically targeted towards the HIV-1 virus and does not work on other viruses.

No, it should not be used as monotherapy due to the risk of resistance development. It is usually used in combination with other antiretroviral medications.

No, you should not stop taking it without your doctor's advice, even if your symptoms improve. This medication helps control the HIV-1 virus but does not cure it. Abrupt discontinuation can lead to a resurgence of the virus.

While this combination significantly reduces the risk of HIV-1 transmission, it does not eliminate it entirely. Continue practicing safe sex and other preventative measures, such as using condoms and regular HIV testing, to minimize the risk of transmission.

Your doctor will monitor your health through regular viral load tests (to measure the amount of HIV-1 virus in your blood) and assessments of immune function (such as CD4 cell counts). These tests will help determine the effectiveness of the medication and guide any necessary adjustments to your treatment.

Yes, it can be used for the management of HIV-1 infection in children who weigh at least 17 kg.

There is no direct evidence to suggest that it affects mood or emotions. However, if you experience changes in your mental health while taking this medication, consult your doctor immediately.

Terms & Conditions


Available medicines for EMTRICITABINE + TENOFOVIR DISOPROXIL FUMARATE
Ricovir Em 200/300 MG Tablet 30
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Tenvir Em Tablet 30
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Truvada 200/300 MG Tablet 30
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Tenof Em Tablet 30
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Tentide Em 200/300 MG Tablet 30
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