Erlotinib is primarily used to manage certain types of non-small cell lung cancer (NSCLC) and pancreatic cancer. It belongs to the kinase inhibitors class of medications.
It can be used as a first-line treatment, maintenance therapy, or second- or later-line treatment for NSCLC with specific EGFR mutations. It is also used in combination with gemcitabine for the first-line management of patients with locally advanced, unresectable, or metastatic pancreatic cancer.
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Erlotinib is a kinase inhibitor.
It functions by blocking the activity of a protein called epidermal growth factor receptor tyrosine kinase, often found in excess in some cancer cells. By doing this, it prevents the growth and spread of these cancer cells, managing their progression.
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Erlotinib is available as a tablet for oral administration.
Erlotinib is meant for adult use only.
Its dosage and duration are to be decided by your doctor. Follow the doctor's instructions closely.
Erlotinib does not have any known contraindications based on medical conditions.
Erlotinib can interact with strong inhibitors of CYP3A4 (such as ketoconazole, itraconazole, voriconazole, and clarithromycin) and strong inducers of CYP3A4 (such as rifampin, phenytoin, and carbamazepine).
Consult your doctor before starting any new medication while taking this medicine.
An overdose may lead to side effects such as mouth sores and nausea. If such symptoms persist or worsen, inform your doctor immediately.
If you miss a dose, take it as soon as you remember and consult your doctor for dosage instructions. Do not double the dose to compensate for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, consult your doctor.
Drinking ample water can help manage diarrhoea and mouth sores.
Eating smaller meals more frequently can help manage appetite loss and nausea.
Erlotinib may cause fatigue and affect your ability to drive or operate heavy machinery. If you feel drowsy or fatigued after taking this medicine, refrain from doing these activities.
Erlotinib should not be used during pregnancy or while breastfeeding, as it may harm the foetus or infant. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before starting this medicine.
Patients with pre-existing liver disease, hepatic impairment, or biliary tract disease should exercise caution and be closely monitored by a doctor when starting Erlotinib.
Patients should avoid grapefruit and grapefruit juice while on Erlotinib as these can increase the risk of its side effects.
Patients taking it are advised to limit sun exposure and use sunscreen due to an increased risk of skin reactions.
Patients are recommended to quit smoking as it can reduce the medicine's effectiveness.
Frequently asked questions
No, Erlotinib is not a steroid. It is a kinase inhibitor.
No specific effect of Erlotinib on sleep is mentioned in the medical literature. However, if you experience related problems when using this medicine, please consult your doctor.
There is no specific information on its impact on fertility. If this is a concern for you, please consult your doctor before starting this treatment.
It should be taken on an empty stomach to enhance absorption and avoid interaction with specific foods.
Yes, it is safe to take daily, if recommended by your doctor. Do not alter or stop your dosage without consulting them.
The time to show effect varies from person to person and could range from weeks to several months, depending on individual response.
Erlotinib should be taken at least one hour before or two hours after a meal. The exact time and dosage can be decided upon consultation with your doctor.
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