The primary use of Etanercept is for managing several autoimmune disorders such as rheumatoid arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis and juvenile idiopathic arthritis. It belongs to the class of biologic medications.
It can also be used in combination with methotrexate in adults with moderate to severe rheumatoid arthritis or psoriatic arthritis.
Redness at the injection site
Itching or pain at the injection site
Headaches
Upper respiratory infections
Abdominal pain
Etanercept is a biologic medication, specifically a Tumour Necrosis Factor (TNF) blocker.
It works by attaching itself to TNF, a body protein that plays a vital role in promoting inflammation. By binding to TNF, Etanercept effectively neutralises its inflammatory actions. This mechanism of action helps to lessen inflammation and associated pain, as well as reducing joint damage in autoimmune diseases such as rheumatoid arthritis and psoriatic arthritis.
Doctor of Medicine
BMS, FMC, MD Resident
Etanercept is available for use via the subcutaneous injection route.
It comes in various formulations including single-dose prefilled syringes, single-dose prefilled autoinjectors, and multiple-dose vials.
Etanercept is meant for both adults and children.
Children should be more than 2 years old to be given this medication.
This medication is contraindicated in patients with a known hypersensitivity to Etanercept or any of its ingredients.
Patients having any active infections should not start with this medicine.
This medicine can interact with anti-TNF agents (such as infliximab) and biologic disease-modifying antirheumatic medicines (like abatacept and anakinra).
It is strongly recommended to avoid live vaccines while using Etanercept.
If an overdose occurs, it may lead to symptoms such as dizziness, fever, itching, and shortness of breath. In such cases, please get immediate medical attention.
If you miss a dose of Etanercept, administer it as soon as you remember. But if it is near the time for your next dose, skip the missed dose and resume your dosing schedule.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor. If you encounter injection site reactions like redness or itching:
Try cooling the area before injecting.
Keep rotating the sites of injection.
For management of upper respiratory infections:
Drink plenty of fluids to ease congestion.
Take adequate rest.
Etanercept may cause side effects such as dizziness and fatigue that can affect your ability to drive or operate heavy machinery. Avoid these activities if you experience such symptoms.
Etanercept should only be used in pregnancy and breastfeeding under the direction of a doctor.
Patients with a history of recurrent infections or prone to infections, such as open cuts, should exercise caution when taking this medicine.
Patients should also inform the doctor if they have had tuberculosis or hepatitis B prior to starting this medication.
Maintain a balanced diet rich in fruits, vegetables, lean protein, and whole grains to support overall health and immunity.
Regular mild to moderate physical activity can help keep joints flexible and strengthen the muscles supporting them, especially for people with rheumatoid arthritis.
Avoiding stress or learning stress-management techniques may also help manage symptoms of autoimmune diseases.
Limiting alcohol intake and quitting smoking can reduce inflammation and benefit overall health.
Frequently asked questions
No, Etanercept is not a steroid. It is a biologic medication used to manage autoimmune disorders.
There is no direct evidence to suggest that Etanercept has an effect on sleep. However, it is essential to consult your doctor if you experience sleep disturbances while on this medication.
No specific studies indicate that Etanercept affects fertility. However, if you are planning to conceive, discuss this with your doctor.
There are no specific diet restrictions associated with the use of Etanercept. Nevertheless, a healthy diet will support overall wellbeing.
Etanercept should be taken as prescribed by your doctor.
Some individuals may notice improvement within 1-2 weeks; however, full benefits are usually seen by 3 months.
Etanercept can be taken at any time that is convenient for you, as long as you are consistent with the day of the week and the time of day.
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