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Formoterol Fumarate + Tiotropium

Uses of Formoterol Fumarate + Tiotropium

  • Formoterol Fumarate + Tiotropium is primarily used for the long-term, once-daily maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It comes under the category of long-acting bronchodilator medicines.

Side effects of Formoterol Fumarate + Tiotropium

  • Nasopharyngitis

  • Cough

  • Dry mouth

  • Headache

  • Dizziness

How Formoterol Fumarate + Tiotropium works

  • Formoterol Fumarate + Tiotropium is a combination bronchodilator.

  • Formoterol Fumarate is a long-acting beta2-adrenergic receptor agonist. It works by stimulating the beta2-adrenergic receptors in the lungs, which leads to the relaxation of the muscles around the airways. It also helps to prevent the release of certain substances that cause allergic reactions and inflammation.

  • Tiotropium is a long-acting muscarinic antagonist. It works by inhibiting the action of a certain chemical called acetylcholine on the receptors in the lungs. This leads to relaxation and widening of the airways, which helps to reduce symptoms such as breathlessness.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Formoterol Fumarate + Tiotropium is available for use as an inhalation spray.

  • This medication is administered via the Respimat inhaler, which is a handheld device designed to deliver a specific dose of the medicine directly to the lungs.

Age and Dose Restrictions

  • This medicine is meant for adults with chronic obstructive pulmonary disease (COPD) and is generally prescribed to individuals who are 18 years of age or older.

Contraindications

  • Formoterol Fumarate + Tiotropium is contraindicated in patients with a history of hypersensitivity to any of its components or to atropine derivatives.

  • It is also contraindicated in patients with narrow-angle glaucoma and those experiencing episodes of acute bronchospasm.

Other Medications to Avoid

  • This combination may interact with other bronchodilators (like salmeterol), additional inhaled corticosteroids (such as beclometasone), and medications affecting the heart rhythm (like digoxin). These interactions can influence the effectiveness and safety of respiratory treatments.

Overdose and Missed Dose

  • An overdose may lead to symptoms such as palpitations, tremors, dry mouth, insomnia, headache, metabolic acidosis, tachycardia, and hypokalemia. If you suspect an overdose, discontinue use and seek immediate medical attention.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and return to your regular dosing schedule. Do not take two doses at the same time.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For dry mouth, sip water regularly throughout the day.

  • If you experience a mild headache, ensure you are adequately hydrated and consider adjusting the timing of your medication after consulting with your doctor.

Use in Driving and Operating Machinery

  • This medicine may cause dizziness or blurred vision. It is advised not to drive or operate heavy machinery until you know how Formoterol Fumarate + Tiotropium affects you.

Use in Pregnancy and Lactation

  • The safety of using Formoterol Fumarate + Tiotropium during pregnancy or while breastfeeding has not been fully established. Consult your doctor if you are pregnant or breastfeeding before beginning treatment with this medicine.

Caution in Other Conditions

  • Patients with moderate to severe renal impairment should be closely monitored due to increased plasma medicine concentrations and reduced clearance when using Formoterol Fumarate + Tiotropium.

  • Individuals with cardiovascular disorders should exercise caution due to the potential cardiac effects of this medication.

Special Dietary and Lifestyle Recommendations

  • Patients diagnosed with COPD are encouraged to cease smoking, as continuing can exacerbate symptoms.

  • Regular physical activity tailored to your capacity can improve respiratory health; however, always consult a doctor before starting a new exercise regime.

  • A diet rich in fruits, vegetables, whole grains, and lean proteins can support overall health and potentially improve outcomes in COPD management.

  • Avoid exposure to pollutants or occupational irritants that could worsen respiratory symptoms.

Frequently asked questions

No, Formoterol Fumarate + Tiotropium is not a steroid. This combination medicine belongs to the class of long-acting bronchodilators, specifically a long-acting beta2-adrenergic receptor agonist (LABA) and a long-acting muscarinic antagonist (LAMA).

There is no evidence of Formoterol Fumarate + Tiotropium directly affecting sleep. However, if you are experiencing unusual sleep patterns or disturbances after starting this medication, please consult your doctor.

Formoterol Fumarate + Tiotropium does not affect fertility. If you have concerns about fertility while taking this medication, it would be best to consult your doctor.

Any specific diet restrictions are not required while taking Formoterol Fumarate + Tiotropium. However, maintaining a balanced diet is always beneficial for overall health.

Yes, it is safe to take Formoterol Fumarate + Tiotropium daily as it is a long-term, once-daily maintenance treatment for chronic obstructive pulmonary disease (COPD).

Formoterol and tiotropium in this combination are rapidly absorbed into the systemic circulation after inhalation, reaching peak plasma concentrations within 5 minutes of dosing.

The best time to take Formoterol Fumarate + Tiotropium will be prescribed by your doctor.

Terms & Conditions


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