Gancyclovir

Dosage Forms Available

• Ganciclovir is available as an intravenous solution, administered through the intravenous route, and as an oral capsule and solution, taken orally.

Age and Dose Restrictions

• Ganciclovir is primarily intended for use in adult patients, particularly those who are immunocompromised.

Contraindications

• Ganciclovir is contraindicated in patients with a known hypersensitivity to Ganciclovir or Valganciclovir.
• It should also be avoided in patients with pre-existing cytopenias or severe renal impairment.

Other Medications to Avoid

• This medicine may interact with other antiviral agents (such as zidovudine), renal clearance-affecting agents (like probenecid), nucleoside analogues (such as didanosine), and immunosuppressants (including mycophenolate mofetil).

Overdose and Missed Dose

• An overdose of Ganciclovir may lead to severe toxic effects such as kidney damage, blood cell count decreases, or neurological symptoms. Immediate medical attention is crucial.
• If you miss a dose of Ganciclovir, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not take two doses at once to make up for the missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To help manage nausea, consider taking your dose with food unless otherwise directed by your doctor.
• If you experience dizziness, ensure to sit or lie down until the feeling passes.

Use in Driving and Operating Machinery

• Ganciclovir can cause dizziness and confusion. It is advised that you do not drive or operate heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• Ganciclovir is not recommended during pregnancy unless absolutely necessary. Women of childbearing potential should use effective contraception during treatment.
• It is also advised to consult your doctor before using Ganciclovir if you are breastfeeding.

Caution in Other Conditions

• Patients with renal impairment should exercise caution when taking Ganciclovir, as the medicine is primarily excreted through the kidneys. Dose adjustments are necessary to prevent toxicity.
• Patients with blood-related problems like anaemia, neutropenia, and thrombocytopenia should inform their doctor before taking this medicine.
• It is also advised to use caution if there is pre-existing liver disease, mental illness, seizures, and eye problems.

Special Dietary and Lifestyle Recommendations

• Ensure adequate hydration to help maintain kidney function while on Ganciclovir treatment.
• Monitor your blood cell counts regularly; include iron-rich foods like spinach, red meat, and beans in your diet to manage the risks of anaemia.
• Maintain good personal hygiene and avoid contact with people who have contagious diseases such as flu or colds.
• Manage stress through relaxation techniques such as yoga or meditation to support overall health.