Gatifloxacin + Prednisolone
Uses of Gatifloxacin + Prednisolone
The primary use of Gatifloxacin + Prednisolone is to manage bacterial eye infections and inflammation. This medicine belongs to the group of antibiotic and corticosteroid medications.
In addition, the medicine is also used for managing conditions like bacterial conjunctivitis, keratitis, corneal ulcers, endophthalmitis, post-operative inflammation of the eye, and other inflammatory ocular conditions where a risk of bacterial infection exists.
Side effects of Gatifloxacin + Prednisolone
Temporary blurred vision
Eye irritation or discomfort
Eyelid swelling
Unpleasant taste in the mouth
Headache
How Gatifloxacin + Prednisolone works
Gatifloxacin, the antibiotic component, blocks enzymes known as DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial replication. By blocking them, gatifloxacin halts bacterial DNA synthesis, disrupting their replication and eliminating the infection-causing bacteria.
Prednisolone, the corticosteroid component, functions by suppressing inflammation. It achieves this by binding to specific receptors in cells called glucocorticoid receptors. This action reduces the production of substances that cause inflammation such as prostaglandins and leukotrienes, ultimately decreasing redness, swelling, and discomfort in the eye.
Certified content
Written By
MD Ayurveda
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Gatifloxacin + Prednisolone is available in the form of ophthalmic suspension (eye drops).
Age and Dose Restrictions
This medicine is meant for adults and children who are older than two years of age.
Contraindications
Gatifloxacin + Prednisolone is contraindicated in patients with known allergies to either gatifloxacin or prednisolone. It is also not suitable for patients with viral diseases of the cornea and conjunctiva like herpes simplex keratitis, vaccinia, and varicella, fungal diseases of ocular structures, untreated parasitic eye infections, or mycobacterial infection of the eye.
Other Medications to Avoid
This combination may interact with other ophthalmic medications like Non-Steroidal Anti-Inflammatory Medicines (NSAIDs) (such as ketorolac), and anticholinesterases used to manage glaucoma (such as neostigmine and physostigmine).
Overdose and Missed Dose
An overdose of Gatifloxacin + Prednisolone may lead to increased side effects such as blurred vision, eye irritation, or increased intraocular pressure. If an overdose occurs, wash your eyes with clean water and get immediate medical attention.
If you miss a dose, take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not instil double the dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage minor side effects such as headache or unpleasant taste in the mouth.
Resting with your eyes closed may help alleviate eye irritation or discomfort.
Use in Driving and Operating Machinery
The use of Gatifloxacin + Prednisolone can cause temporary blurred vision. Avoid driving or operating heavy machinery until your vision is clear.
Use in Pregnancy and Lactation
Gatifloxacin + Prednisolone falls under pregnancy category C. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution should be exercised when using this medicine during breastfeeding.
Caution in Other Conditions
Caution is advised when administering Gatifloxacin + Prednisolone to patients with glaucoma due to the potential rise in intraocular pressure.
Special Dietary and Lifestyle Recommendations
Wear sunglasses when going outdoors to protect your eyes from dust and other foreign particles.
Regular eye check-ups are recommended to monitor your eye health and the effect of the medication.
Frequently asked questions
Is Gatifloxacin + Prednisolone a steroid?
Gatifloxacin + Prednisolone is a combination of two different types of medications. One of them, Prednisolone, is indeed a type of steroid known as a corticosteroid. The other component, Gatifloxacin, is not a steroid; it is an antibiotic medication that helps to fight against bacterial infections.
Can Gatifloxacin + Prednisolone cause weight gain?
Gatifloxacin + Prednisolone is generally applied topically as an eye drop and not absorbed through the digestive system, so it is unlikely to cause systemic side effects such as weight gain. However, individual reactions may vary and any concerns should be discussed with your doctor.
Can Gatifloxacin + Prednisolone affect menstruation or mood?
There is no documented evidence suggesting that Gatifloxacin + Prednisolone affects menstruation or mood when used as directed for treating eye conditions. However, if you notice any unusual changes while using this medication, consult your doctor.
Is there an alternative to Gatifloxacin + Prednisolone for eye infections and inflammation?
Yes, there are other types of eye drops that contain different antibiotics and steroids which can also be used to manage eye infections and inflammation. The doctor will prescribe the most suitable one based on your specific condition and needs.
Can I use Gatifloxacin + Prednisolone for viral eye infections?
No, Gatifloxacin + Prednisolone should not be used for viral eye infections as it contains an antibiotic, Gatifloxacin, which only works against bacterial infections. It is important to use the right medicine for your condition.
How long should I use Gatifloxacin + Prednisolone for my eye infection?
The duration of treatment with Gatifloxacin + Prednisolone depends on the type and severity of your eye infection. Your doctor will give instructions on how long to use this medicine. Always follow your doctor's advice.
Can I use Gatifloxacin + Prednisolone while wearing contact lenses?
It is generally advised to remove contact lenses before applying Gatifloxacin + Prednisolone eye drops, and to wait at least 15 minutes after applying the drops before reinserting the contact lenses.
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