Glycerin
Uses of Glycerin
Glycerin is primarily used to manage various skin conditions such as dry, rough or scaly skin, minor skin irritations, skin burns from radiation therapy, psoriasis and eczema. It belongs to the group of humectants in skincare products.
In addition to its dermatological uses, Glycerin is also used to manage occasional constipation and acts as a demulcent in certain cough preparations.
Side effects of Glycerin
Skin irritation
Redness
Burning sensation
Stinging sensation
Rectal discomfort or burning with suppository use
How Glycerin works
Glycerin is a natural humectant and emollient.
It hydrates the skin by drawing water from the air and deeper layers to the outer skin, forming a protective barrier to prevent moisture loss. While in the gut, it attracts water into the intestines, softening stools and stimulating bowel movements, thus acting as a mild laxative.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Glycerine can be taken orally (syrup, solutions), applied topically (eye drops, creams, lotions, ointments), intravenous (infusion) and rectal (suppository) routes.
Age and Dose Restrictions
Glycerin can be used in both adults and children with appropriate dosage.
Contraindications
Glycerin is contraindicated for those with known hypersensitivity or allergy to it or its ingredients, or of you have diabetes.
Other Medications to Avoid
Glycerin, when used topically or orally, generally has a low potential for drug interactions, but when used in specific formulations, it may interact with topical retinoids (tretinoin). Glycerin, if ingested in large amounts, may interact with diuretics (like hydrochlorothiazide, and oral hypoglycemic agents.
Overdose and Missed Dose
An overdose of Glycerin could potentially lead to side effects like headaches, dizziness, nausea, vomiting, and diarrhoea. If you suspect an overdose, seek medical advice immediately.
If you forget to apply or take a dose of Glycerin as per your schedule, do so as soon as you remember. However, if it is close to the time for your next dose, skip the missed one and continue with your regular dosing schedule.
Management of Side Effects
Most side effects of Glycerin are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If Glycerin causes skin irritation when used topically, stop using it and wash the affected area with water.
When used as a suppository, Glycerin may cause temporary rectal discomfort or burning. Consult your doctor is the discomfort persists.
Taking the medication after meals and drinking plenty of water can help reduce nausea.
Use in Driving and Operating Machinery
Glycerin does not generally affect your ability to drive or operate heavy machinery. However, in case you experience any dizziness or other side effects that might affect your ability to concentrate, avoid such activities until you feel better.
Use in Pregnancy and Lactation
Caution is advised while taking Glycerin during pregnancy or while breastfeeding.
Caution in Other Conditions
Individuals with severe dehydration, heart and kidney should exercise caution when taking oral Glycerin as it may worsen their condition. Consultation with a doctor is recommended before starting usage in such cases.
Special Dietary and Lifestyle Recommendations
Regularly drinking plenty of water can help prevent constipation, reducing the need for laxatives like Glycerin.
For skincare, protecting your skin from excessive sun exposure and keeping it well-moisturised can support the beneficial effects of topical Glycerin.
Frequently asked questions
Is Glycerin a natural or synthetic ingredient?
Glycerin, or glycerol, is a naturally occurring compound derived from vegetable oils or animal fats, but it can also be produced synthetically.
Can Glycerin cause any allergic reactions?
Yes, though rare, some people may experience an allergic reaction to glycerin, with symptoms like rash, itching, swelling, severe dizziness, or trouble breathing; if these occur, discontinue use and consult your doctor immediately.
Does Glycerin provide immediate relief for dry skin?
As a humectant, Glycerin attracts water to the skin's upper layer, providing immediate relief to dryness, though improvement time can vary with skin type and dryness severity.
Is it safe to use Glycerin daily?
Yes, when used as directed, Glycerin is generally safe for daily use. However, if you have any concerns, consult your doctor.
Can Glycerin be used on all types of skin?
Glycerin is generally safe for all skin types, but if you have extremely sensitive skin or a history of allergic reactions, perform a patch test before full application.
Can Glycerin be used on open wounds?
While glycerin can hydrate and promote healing, it should not be used on deep wounds, animal bites, or serious burns unless directed by a doctor. Always consult your doctor before applying any medication to an open wound.
How much time does Glycerin take to work?
Glycerin's effects can be noticed almost immediately when used topically, especially in improving skin hydration. For constipation relief, Glycerin suppositories typically produce a bowel movement within 15 minutes to 1 hour after administration.
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