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Hydralazine

Uses of Hydralazine

  • The primary use of Hydralazine is for the management of high blood pressure (hypertension). It belongs to the category of medicines known as vasodilators.

  • In some cases, it may also be used in the management of heart failure.

Side effects of Hydralazine

  • Headaches

  • Nausea and vomiting

  • Heart palpitations

  • Dizziness and fatigue

  • Skin rash

How Hydralazine works

  • Hydralazine is a vasodilator. It works by acting directly on the muscles in the walls of the arteries, which are the large blood vessels that carry blood from the heart to all parts of the body. This action causes these muscles to relax, and consequently, the arteries widen or dilate. When the arteries dilate, blood can flow through them more easily.

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Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Hydralazine is available via oral route (tablets). It can also be administered intravenously, in a hospital or medical clinic, under the supervision of a doctor.

Age and Dose Restrictions

  • Hydralazine is primarily intended for adults of age above 18 years.

Contraindications

  • The use of Hydralazine is contraindicated in patients who have known allergies to the medication or any of its components.

  • It should not be used by individuals with coronary artery disease or mitral valve rheumatic heart disease.

Other Medications to Avoid

  • Hydralazine can interact with MAO inhibitors (such as phenelzine and tranylcypromine), some antidepressants (like amitriptyline and imipramine), and other vasodilators and antihypertensives (like nifedipine and losartan).

Overdose and Missed Dose

  • Overdosing on Hydralazine may cause severe hypotension, increased heart rate, shock, and potentially stroke. Immediate medical attention is required.

  • In case you miss a dose of this medication, take it as soon as you recall. However, if it is near the time for your next dose, simply skip the missed dose and continue with your regular schedule. Never double up on doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage potential side effects of dizziness or lightheadedness, it is recommended to get up slowly when transitioning from a lying or sitting position to standing. This allows your body time to adjust and helps to prevent falls.

  • Drinking plenty of fluids can help manage potential side effects such as headaches and nausea.

Use in Driving and Operating Machinery

  • Hydralazine can cause dizziness and fatigue, affecting your ability to drive or operate machinery. Therefore, avoid such activities until you are sure about how this medication affects you.

Use in Pregnancy and Lactation

  • It is advised to consult with your doctor if you are pregnant or nursing before using this medication.

Caution in Other Conditions

  • Patients with cerebrovascular disease or kidney impairment should take Hydralazine with caution.

Special Dietary and Lifestyle Recommendations

  • Limiting salt intake can enhance the effectiveness of Hydralazine in managing high blood pressure.

  • Consuming a healthy, balanced diet rich in fruits, vegetables, lean proteins and whole grains can help manage underlying hypertension.

  • Regular physical activity, as recommended by a doctor, can also aid in managing high blood pressure.

Frequently asked questions

No, Hydralazine is not a steroid. It is a vasodilator medication used to manage hypertension.

Hydralazine is not associated with affecting sleep. However, some patients might experience fatigue as a side effect, which could potentially affect one's sleep schedule.

Hydralazine is not directly associated with affecting fertility. If you have concerns about this issue, it is best to consult with your doctor.

Yes, when prescribed by a doctor, it is safe to take Hydralazine daily. The medicine should be taken exactly as per your doctor's instructions.

Hydralazine typically starts working within a few minutes of oral administration, with peak effects seen in a few hours.

The best time to take Hydralazine will depend on your treatment plan as discussed with your doctor.

While there are natural methods to control blood pressure like exercise and dietary modifications, it is important to note that they cannot replace prescribed medication like Hydralazine in managing high blood pressure.

Terms & Conditions


Hydralazine in other salts

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