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Hydrochlorothiazide + Valsartan

Uses of Hydrochlorothiazide + Valsartan

  • Hydrochlorothiazide + Valsartan is primarily used for the management of high blood pressure (hypertension), and it falls in the category of medications known as thiazide diuretics and angiotensin II receptor blockers.

Side effects of Hydrochlorothiazide + Valsartan

  • Dizziness

  • Headache

  • Fatigue

  • Nausea

  • Muscle cramps

How Hydrochlorothiazide + Valsartan works

  • Hydrochlorothiazide is a thiazide diuretic. It increases the amount of urine produced, which helps your body get rid of excess salt and water. This process reduces the volume of fluid flowing through your blood vessels, thereby lowering your blood pressure.

  • Valsartan is an Angiotensin II Receptor Blocker (ARB). It works by blocking the action of a natural hormone known as angiotensin II, which typically causes your blood vessels to narrow. By preventing this, Valsartan allows your blood vessels to relax and widen, contributing to the reduction of blood pressure.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Hydrochlorothiazide + Valsartan is available as tablets, to be administered orally.

Age and Dose Restrictions

  • The Hydrochlorothiazide + Valsartan combination is meant for adult usage.

Contraindications

  • This combination is not recommended for patients with known allergies to hydrochlorothiazide or valsartan.

Other Medications to Avoid

  • Hydrochlorothiazide + Valsartan can interact with diuretics (e.g., chlorthalidone), mood stabilisers (e.g., lithium), heart failure medications (e.g., digoxin), bile acid sequestering agents (e.g., cholestyramine) cholesterol-lowering medication (e.g., colestipol), nonsteroidal anti-inflammatory medications (e.g., ibuprofen, diclofenac), potassium supplements (e.g., potassium chloride, potassium citrate), and potassium-containing salt substitutes.

Overdose and Missed Dose

  • Overdose of Hydrochlorothiazide + Valsartan may result in symptoms like extreme dizziness and fainting. In such cases, immediate medical help should be sought.

  • If you forget to take this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and usually resolve upon stopping the medication. However, if any severe side effects or worsening of symptoms are noticed, consult your doctor immediately.

  • Drinking plenty of water can help manage common side effects like dizziness and headache.

  • Resting or sitting down after taking this medication can also help manage dizziness.

Use in Driving and Operating Machinery

  • This combination may affect your ability to drive or operate heavy machinery due to potential side effects like dizziness. Refrain from these activities if you feel dizzy after taking this medication.

Use in Pregnancy and Lactation

  • Hydrochlorothiazide + Valsartan is not recommended during pregnancy or lactation unless advised by your doctor. Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with kidney disease, liver disease, gout, lupus, and diabetes may need to exercise caution when taking Hydrochlorothiazide + Valsartan.

Special Dietary and Lifestyle Recommendations

  • Maintain a low-salt, balanced diet to complement the blood pressure lowering effect of Hydrochlorothiazide + Valsartan.

  • Avoid consuming excessive amounts of potassium as this can lead to hyperkalaemia, a condition characterized by high potassium levels in the blood.

Frequently asked questions

No, Hydrochlorothiazide + Valsartan is not a steroid. It is a combination of two medicines, a thiazide diuretic (water pill) and an angiotensin II receptor blocker (ARB).

No research data is available on this combination medication affecting sleep. However, some people may experience dizziness which could potentially impact sleep. Always consult your doctor if you have concerns.

While there is no specific evidence in the research literature about Hydrochlorothiazide + Valsartan impacting fertility, it is always best to discuss this with your doctor if you are planning to conceive.

No, Hydrochlorothiazide + Valsartan does not typically cause weight gain. However, individual responses may vary. Always consult your doctor if you experience any unexpected changes in your weight.

Yes, Hydrochlorothiazide + Valsartan can be taken daily under the guidance of your doctor. Always follow your doctor's instructions regarding dosage and frequency.

The combination of Hydrochlorothiazide + Valsartan starts to lower blood pressure within a few hours after you take it.

The elimination half-life of hydrochlorothiazide is about 6-15 hours and that of valsartan is about 6 hours. However, the exact duration it stays in your system can vary based on several factors including kidney function, age, metabolic rate and body weight.

Terms & Conditions


Available medicines for HYDROCHLOROTHIAZIDE + VALSARTAN
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