Hydrocortisone

Dosage Forms Available

• Hydrocortisone is available as tablets, capsules, and liquid suspensions and is taken orally.

Age and Dose Restrictions

• Hydrocortisone is typically prescribed for adults.

• Its use in children is limited due to potential side effects such as growth retardation.

Contraindications

• This medication is contraindicated in patients with active fungal infections, active tuberculosis, eye infections caused by the herpes simplex virus, severe osteoporosis, severe mental health conditions, kidney problems, and liver diseases. It is also contraindicated in individuals receiving any live virus vaccination.

Other Medications to Avoid

• Hydrocortisone may interact with CYP3A4 inducers (e.g., phenytoin, rifampin), CYP3A4 inhibitors (e.g., ketoconazole, ritonavir), NSAIDs (e.g., aspirin, ibuprofen), oral anticoagulants (e.g., warfarin), and antidiabetic agents (e.g., metformin).

Overdose and Missed Dose

• Taking too much Hydrocortisone can lead to symptoms such as weight gain, thinning skin, and changes in the shape or location of body fat. If you think you've taken too much, consult your doctor immediately.

• If you miss a dose, take it as soon as you remember. But if it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

• Most side effects of Hydrocortisone are temporary, and they go away once you stop taking this medicine. However, if any side effects become severe or if your symptoms worsen, please contact your doctor.

Use in Driving and Operating Machinery

• Hydrocortisone can sometimes cause dizziness or changes in vision. If you experience these side effects, do not drive or operate heavy machinery until these effects have worn off.

Use in Pregnancy and Lactation

• If you are pregnant or breastfeeding, consult your doctor before starting Hydrocortisone. It should only be used if the potential benefits outweigh the risks.

Caution in Other Conditions

• If you have kidney disease or liver disease, you should exercise caution when taking Hydrocortisone. Your doctor may need to adjust your dose to suit your condition.

Special Dietary and Lifestyle Recommendations

• While taking Hydrocortisone, it's important to follow a balanced diet rich in calcium and vitamin D to counteract the risk of bone loss (osteoporosis).

• Limiting salt intake can help manage fluid retention and high blood pressure, which are potential side effects of Hydrocortisone.

• Regular exercise can also help maintain bone strength and manage weight gain associated with Hydrocortisone use.