Hydroxyprogesterone

Dosage Forms Available

• Hydroxyprogesterone can be administered intramuscularly (injection).

Age and Dose Restrictions

• This medicine is meant for adult women who are pregnant and have a history of premature birth.

Contraindications

• Hydroxyprogesterone is contraindicated in women with a history or current diagnosis of breast cancer or other hormone-sensitive cancers and acute liver disease.

• Women with undiagnosed abnormal vaginal bleeding, liver problems or disease, and a history of allergic reactions to Hydroxyprogesterone or any of its components should not take this medicine. It is also contraindicated in cases of missed abortion and patients with a history of blood clots or clotting disorders.

Other Medications to Avoid

• Hydroxyprogesterone can potentially interact with enzyme inducers or inhibitors (such as St John's Wort or fluconazole).

Overdose and Missed Dose

• Overdose is unlikely since Hydroxyprogesterone is administered by a healthcare professional. If an overdose occurs, supportive and symptomatic treatment should be provided.

• For a missed dose, consult your doctor for further guidance. The dose should never be doubled to compensate for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless, resolving when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

• Drinking plenty of water can help manage common side effects such as nausea, vomiting, and diarrhoea.

• Resting and avoiding sudden movements can help manage headaches.

Use in Driving and Operating Machinery

• Hydroxyprogesterone may affect your ability to drive or operate machinery. Consult your doctor if you experience these symptoms.

Use in Pregnancy and Lactation

• Hydroxyprogesterone is a pregnancy category B medicine. It is used in pregnancy but should be used under the supervision of a doctor.

• Small amounts may pass into breast milk but are not expected to be harmful to the nursing baby. Risks and benefits during lactation should be discussed with the prescribing doctor.

Caution in Other Conditions

• Patients with a history of blood clots or clotting disorders should exercise caution when taking Hydroxyprogesterone.

• Hydroxyprogesterone should also be used with caution in women with conditions that could be affected by fluid retention, such as asthma, migraines, epilepsy, heart disease.

Special Dietary and Lifestyle Recommendations

• Regular antenatal check-ups are recommended for monitoring the progress of the pregnancy and early detection of any complications.