Ibrutinib

Expert Advice

Dosage Forms Available

• Ibrutinib is available for oral administration (oral suspension, capsules and tablets).

Age and Dose Restrictions

• Ibrutinib is intended for use by adults. It is approved for use in children 1 year and older with cGVHD, but its safety and efficacy in children under 1 year are unknown.

Contraindications

• Ibrutinib is contraindicated in patients with a known hypersensitivity to Ibrutinib or any of its components.

Other Medications to Avoid

• Ibrutinib can interact with strong CYP3A4 inhibitors (such as ketoconazole, itraconazole and clarithromycin).

Overdose and Missed Dose

• An overdose of Ibrutinib could potentially result in severe side effects such as heart rhythm problems or bleeding episodes. In case of suspected overdose, seek immediate medical attention.

• If you forget to take your dose of Ibrutinib, take it as soon as you remember on the same day. If it is already the next day, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of fluids can help manage common side effects like diarrhoea and nausea.

• If you experience fatigue, try to get adequate rest and avoid strenuous activities.

• Maintain good oral hygiene to manage mouth sores or ulcers.

Use in Driving and Operating Machinery

• Ibrutinib may cause dizziness and fatigue, which could affect your ability to drive or operate heavy machinery. Avoid these activities if you experience these side effects.

Use in Pregnancy and Lactation

• It is advisable to consult a doctor before using Ibrutinib during pregnancy and breastfeeding.

Caution in Other Conditions

• Patients with liver disease should have their liver function monitored regularly while taking Ibrutinib.

• Patients with a history of heart disease should be closely monitored for heart rate irregularities during treatment with Ibrutinib.

Special Dietary and Lifestyle Recommendations

• Regular physical activity can promote better overall health and well-being, which can be beneficial for patients managing a chronic condition such as cancer.

• A balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats can support overall health and immunity.

Frequently asked questions

Terms & Conditions