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Ibrutinib

Uses of Ibrutinib

  • Ibrutinib is primarily used in the management of certain types of blood cancers, including Mantle Cell Lymphoma (MCL), Chronic Lymphocytic Leukemia (CLL), and Waldenström's Macroglobulinemia. It falls under the class of Bruton's Tyrosine Kinase (BTK) inhibitors.

Side effects of Ibrutinib

  • Diarrhoea

  • Fatigue

  • Nausea

  • Mild bruising

  • Muscle and joint pain

How Ibrutinib works

  • Ibrutinib is a Bruton's tyrosine kinase (BTK) inhibitor. It works by obstructing the action of BTK, an enzyme that plays a critical role in the development and survival of B-cells, a type of white blood cell. This blocking action of Ibrutinib slows down the growth and spread of cancerous B cells, thereby helping to manage the progression of blood cancers.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Divya Chauhan
Dr. Divya Chauhan Medical Writer & Reviewer| 6 years

BAMS, APG, PG

Expert Advice

Dosage Forms Available

  • Ibrutinib is available for oral administration (oral suspension, capsules and tablets).

Age and Dose Restrictions

  • Ibrutinib is intended for use by adults. It is approved for use in children 1 year and older with cGVHD, but its safety and efficacy in children under 1 year are unknown.

Contraindications

  • Ibrutinib is contraindicated in patients with a known hypersensitivity to Ibrutinib or any of its components.

Other Medications to Avoid

  • Ibrutinib can interact with strong CYP3A4 inhibitors (such as ketoconazole, itraconazole and clarithromycin).

Overdose and Missed Dose

  • An overdose of Ibrutinib could potentially result in severe side effects such as heart rhythm problems or bleeding episodes. In case of suspected overdose, seek immediate medical attention.

  • If you forget to take your dose of Ibrutinib, take it as soon as you remember on the same day. If it is already the next day, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids can help manage common side effects like diarrhoea and nausea.

  • If you experience fatigue, try to get adequate rest and avoid strenuous activities.

  • Maintain good oral hygiene to manage mouth sores or ulcers.

Use in Driving and Operating Machinery

  • Ibrutinib may cause dizziness and fatigue, which could affect your ability to drive or operate heavy machinery. Avoid these activities if you experience these side effects.

Use in Pregnancy and Lactation

  • It is advisable to consult a doctor before using Ibrutinib during pregnancy and breastfeeding.

Caution in Other Conditions

  • Patients with liver disease should have their liver function monitored regularly while taking Ibrutinib.

  • Patients with a history of heart disease should be closely monitored for heart rate irregularities during treatment with Ibrutinib.

Special Dietary and Lifestyle Recommendations

  • Regular physical activity can promote better overall health and well-being, which can be beneficial for patients managing a chronic condition such as cancer.

  • A balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats can support overall health and immunity.

Frequently asked questions

No natural alternatives to Ibrutinib have been proven to be effective for its indicated uses. You should not switch or stop your prescribed medication without consulting your doctor.

No, Ibrutinib is not a steroid. It belongs to a class of medicines known as Bruton's tyrosine kinase (BTK) inhibitors, which are used to manage certain types of blood cancers.

Ibrutinib is not associated with affecting mood. However, any changes in mood or behaviour while taking this medication should be reported to your doctor.

Ibrutinib is not directly associated with affecting fertility. Before starting this medication, discussing potential risks and benefits with your doctor is important.

Ibrutinib is not associated with affecting menstruation. However, all changes related to the menstrual cycle while on this medication should be reported to your doctor.

Yes, Ibrutinib is safe for vegetarians and vegans. However, if you have any specific dietary concerns, it is always best to consult your doctor before starting any new medication.

The exact time that Ibrutinib stays in your system can vary depending on various factors such as your metabolism, general health, and other medications you might be taking. You should consult your doctor for more precise information.

Terms & Conditions

Available medicines for IBRUTINIB
Ibrunat Capsule 30
Ibrunat Capsule 30
Natco Pharma Ltd
Pack of 30 Units
₹7790.00
MRP ₹9500.00
18.00% OFF
Ibrukem 140 MG Capsule 30
Ibrukem 140 MG Capsule 30
Alkem Laboratories Ltd.
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₹7380.00
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Nitib 140mg Capsule 30
Nitib 140mg Capsule 30
Hetero Healthcare Ltd
Pack of 30 Units
₹7954.00
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18.00% OFF
Ib Tib Capsule 30
Ib Tib Capsule 30
Cadila Pharmaceuticals Ltd
Pack of 30 Units
₹6477.18
MRP ₹7899.00
18.00% OFF
Ibrushil 140 MG Capsule 30
Ibrushil 140 MG Capsule 30
Shilpa Medicare Ltd
Pack of 30 Units
₹7372.62
MRP ₹8991.00
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Imbruvica 140 MG Capsule 90
Imbruvica 140 MG Capsule 90
Johnson & Johnson
Pack of 90 Units
₹268960.00
MRP ₹328000.00
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Bdbrut 140 MG Capsule 30
Bdbrut 140 MG Capsule 30
Bdr Pharmaceuticals Internationals Pvt. Ltd
Pack of 30 Units
₹5904.00
MRP ₹7200.00
18.00% OFF
Imbruvica 140 MG Capsule 120
Imbruvica 140 MG Capsule 120
Johnson & Johnson
Pack of 120 Units
₹357520.00
MRP ₹436000.00
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