Imatinib Mesylate
Uses of Imatinib Mesylate
Imatinib Mesylate is primarily used for the management of various types of leukaemia, blood disorders, and tumours. It belongs to the class of medicines known as tyrosine kinase inhibitors.
Side effects of Imatinib Mesylate
Nausea and vomiting
Muscle cramps and pain
Abdominal pain
Rash
How Imatinib Mesylate works
Imatinib Mesylate is a tyrosine kinase inhibitor.
It primarily works by blocking the action of specific enzymes, particularly BCR-ABL in leukaemia cells and KIT in certain types of tumour cells. These enzymes are involved in the growth and multiplication of cancer cells.
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Written By
BDS, MDS
Reviewed By
Bachelor of Dental Surgery
Expert Advice
Dosage Forms Available
Imatinib Mesylate can be taken orally (tablet).
Age and Dose Restrictions
Imatinib Mesylate can be used in adults and children above 2 years when prescribed.
Contraindications
Imatinib Mesylate is contraindicated in patients with known hypersensitivity to Imatinib or any of its inactive ingredients.
Other Medications to Avoid
Imatinib Mesylate may interact with CYP3A4 inducers (such as rifampin and phenytoin), CYP3A4 inhibitors (such as ketoconazole and erythromycin).
Overdose and Missed Dose
An overdose of Imatinib Mesylate may aggravate the side effects and can lead to severe complications. If an overdose occurs, seek emergency medical help.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help cope with side effects like nausea and vomiting.
Muscle pain or weakness can be managed with gentle stretching exercises.
Use in Driving and Operating Machinery
Using Imatinib Mesylate can cause dizziness or sleepiness in some patients. You are advised not to drive or operate heavy machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
Imatinib Mesylate is not advised for pregnant women as it can cause harm to the foetus. It is also not recommended for breastfeeding mothers as it is not known if Imatinib Mesylate passes into breast milk.
Caution in Other Conditions
Patients with liver disease or kidney disease should use Imatinib Mesylate with caution. Dose adjustments may be necessary for these patients.
Special Dietary and Lifestyle Recommendations
Regular blood tests may be required to monitor the levels of blood cells and liver function during treatment.
Frequently asked questions
Is Imatinib Mesylate a steroid?
No, Imatinib Mesylate is not a steroid. It is a type of medication known as a 'tyrosine kinase inhibitor', which is primarily used in the management of various types of cancer.
Can Imatinib Mesylate affect sleep?
Imatinib Mesylate is not directly associated with affecting sleep. However, side effects like fatigue and muscle weakness may indirectly interfere with sleep. Always consult your doctor if you experience unusual sleep patterns while using this medicine.
What impact does Imatinib Mesylate have on fertility?
Imatinib Mesylate might affect fertility in both men and women. Therefore, if you plan to have a child, it is important to discuss this with your doctor.
Is it safe to take Imatinib Mesylate every day?
Imatinib Mesylate should be taken as advised by your doctor. The daily safety depends on the type of disease being managed, the patient's overall health condition, and the response to treatment.
How long does Imatinib Mesylate take to work?
The time taken for Imatinib Mesylate to work can vary depending on the type of disease being managed. It is crucial to take the medicine exactly as prescribed by your doctor and regularly monitor your health condition.
What is the best time to take Imatinib Mesylate?
Imatinib Mesylate should be taken with food. However, the best time to take it can vary depending on your individual health condition and medical history. Always consult your doctor for detailed instructions.
Can I stop taking Imatinib Mesylate if I am feeling better?
No, you should not stop taking Imatinib Mesylate without consulting your doctor, even if you feel better. It is important to continue taking your medication for the full duration prescribed by your doctor.
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