Inositol Nicotinate
Uses of Inositol Nicotinate
The primary use of Inositol Nicotinate is for the management of Raynaud's syndrome, a condition that causes blood vessels in fingers and toes to narrow in response to cold temperatures or stress.
Secondary uses include lowering high cholesterol levels, reducing high blood pressure, managing symptoms of peripheral artery disease, decreasing anxiety, preventing migraines and headaches, aiding in restless legs syndrome, and managing skin conditions like psoriasis and scleroderma.
Side effects of Inositol Nicotinate
Flushing and warmth in the face and neck
Stomach upset
Nausea and vomiting
Headache and dizziness
Allergic reactions like rash, itching, or hives
How Inositol Nicotinate works
Inositol Nicotinate is a vasodilator and a form of vitamin B3.
It is converted into niacin in the body, which plays a vital role in energy metabolism, amino acid metabolism, and toxin removal.
It also triggers the release of histamine, which leads to the relaxation and widening of blood vessels. This allows more blood, oxygen, and nutrients to reach areas with poor circulation.
The niacin component also influences lipid metabolism, assisting in the reduction of cholesterol and triglyceride levels.
Together, these actions help manage Raynaud's syndrome and potentially improve conditions like high cholesterol, high blood pressure, peripheral artery disease, and other related issues.
Certified content
Written By
BDS, MDS
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Inositol Nicotinate is available in the form of oral tablets and capsules.
Age and Dose Restrictions
This medicine is meant for use by adults. It is not typically prescribed for children or adolescents.
Contraindications
This medicine is contraindicated in patients with active liver disease or unexplained elevated liver enzymes.
Other Medications to Avoid
This medicine may interact with diabetes medicines (such as metformin and glibenclamide), anticoagulants and antiplatelet medicines (like warfarin and clopidogrel), bile acid sequestrants (such as cholestyramine), blood pressure medications (like amlodipine and lisinopril), and statins (including simvastatin and atorvastatin).
Overdose and Missed Dose
An overdose may lead to symptoms such as severe flushing, dizziness, rapid heartbeat, and possibly gastrointestinal distress. If you suspect an overdose, it is crucial to seek immediate medical attention.
If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage flushing or warmth, consider taking the medicine during cooler parts of the day.
For mild stomach upset, taking the medication with food might help alleviate discomfort.
Use in Driving and Operating Machinery
Inositol Nicotinate can cause dizziness or lightheadedness in some individuals. If you experience these symptoms, it is advisable not to drive or operate heavy machinery.
Use in Pregnancy and Lactation
The safety of Inositol Nicotinate in pregnancy and lactation has not been fully established. Therefore, it is recommended to consult your doctor before using this medication if you are pregnant or breastfeeding.
Caution in Other Conditions
Caution is advised for those with kidney disease or gallbladder disease when using this medicine. Discuss your medical history with your doctor to ensure it is safe for you.
Individuals with a history of ulcer disease or diabetes should consult their doctor before using this medicine as it may exacerbate these conditions.
Special Dietary and Lifestyle Recommendations
Incorporate a diet low in saturated fats and high in fruits, vegetables, and whole grains to help manage cholesterol levels.
Maintain a regular sleep schedule to help manage stress and potentially reduce symptoms of Raynaud's syndrome.
Dress warmly in cold weather to prevent episodes triggered by cold exposure if using this medicine to manage Raynaud's syndrome.
Frequently asked questions
Is Inositol Nicotinate a steroid?
No, it is not a steroid. It is a compound made by combining inositol with niacin (vitamin B3).
Does the Inositol Nicotinate have any effect on sleep?
Currently, there is no scientific evidence to suggest that it has an effect on sleep. If you have concerns, please consult your doctor.
Will Inositol Nicotinate affect fertility?
There is no documented evidence indicating that it affects fertility. However, always share your health concerns with your doctor.
Are there any particular diet restrictions while taking Inositol Nicotinate?
No specific diet restrictions have been mentioned while taking Inositol Nicotinate. Still, it is advisable to follow a balanced diet and maintain a healthy lifestyle.
Is it safe to take Inositol Nicotinate daily?
Yes, it is safe to take it daily as per the recommendation of your doctor.
How much time does Inositol Nicotinate take to work?
The time for Inositol Nicotinate to work can vary depending on the condition being managed, but for Raynaud's syndrome, it may take several weeks of daily use before improvements are noticed.
What is the best time to take Inositol Nicotinate?
It should be taken only at the time suggested by the doctor. In addition, taking it consistently at the same time helps maintain a steady level of the medicine in your body.
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