Insulin Aspart is used primarily to control high blood sugar levels in individuals with Type 1 and Type 2 diabetes mellitus. It belongs to the rapid-acting insulin analogue group.
Hypoglycemia (low blood sugar)
Injection site reactions
Weight gain
Allergic reactions
Hypokalemia (low blood potassium)
Insulin Aspart is a rapid-acting insulin analogue.
It mimics the body's natural insulin, but acts quicker and for a shorter duration.
It operates by stimulating body tissues to take in glucose from the bloodstream, thereby lowering blood sugar levels.
When it binds to insulin receptors on cells, it triggers several effects: it increases glucose uptake into muscle and fat cells, reduces glucose production by the liver, inhibits fat and protein breakdown, and boosts protein synthesis.
The Aspart molecule is a modified version of human insulin designed for faster absorption from the injection site. This enables it to closely imitate the natural insulin response to meals.
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Insulin Aspart is available in solution form for managing high blood sugar levels.
The medicine is administered through the subcutaneous route, which involves injecting it under the skin.
It is suitable for use in both adults and children. It can be used in children aged of two years and older.
This medicine is contraindicated in individuals who have experienced hypersensitivity reactions to Insulin Aspart or any of its components.
It is also contraindicated during instances of hypoglycemia, where blood sugar levels are abnormally low.
This medicine can interact with oral antidiabetic agents (such as sulfonylureas and meglitinides), some antihyperglycemics (like pramlintide), corticosteroids (like prednisone), diuretics (like thiazides and loop diuretics), atypical antipsychotics (like risperidone and olanzapine), sympathomimetic agents (such as pseudoephedrine and phentermine), some anti-infectives like pentamidine, thyroid hormones (like levothyroxine), and beta-blockers (such as atenolol and propranolol).
An overdose might lead to severe hypoglycemia, which can cause symptoms such as shaking, dizziness, sweating, and confusion. In severe cases, it may lead to unconsciousness or seizures. Immediate medical attention should be sought.
If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next dose. In that case, the missed dose should be skipped to avoid the risk of hypoglycemia. Double dosing should be avoided.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage hypoglycemia, consume a fast-acting source of sugar, such as glucose tablets or juice.
Injection site reactions such as redness or swelling can typically be managed by rotating the injection site with each dose.
It typically does not directly affect your ability to drive or operate heavy machinery. However, caution should be exercised in cases of hypoglycemia, which could impair cognitive abilities.
This medicine can be used during pregnancy; however, insulin requirements may change during pregnancy. It is crucial to consult a doctor for appropriate management.
It is not known whether it passes into breast milk. Consultation with a doctor is advised for lactating mothers.
Caution is advised when using Insulin Aspart in patients with renal or hepatic impairment as they may be more susceptible to hypoglycemia. Dose adjustments might be necessary to account for altered insulin metabolism in these conditions.
Consistent monitoring of blood glucose levels is crucial for appropriately adjusting dietary intake and insulin dosages.
Avoid consumption of simple sugars and highly processed foods to prevent spikes in blood sugar levels.
Maintaining a healthy body weight is recommended to improve insulin sensitivity.
Frequently asked questions
Yes, weight gain is a potential side effect of this medicine. Unexplained changes in weight, either weight loss or gain, should be reported to your doctor.
Although rare, this medicine can cause allergic reactions in some people. Symptoms include rashes, itching, swelling or severe dizziness. Anyone experiencing these symptoms should seek immediate medical attention.
No, it is not a steroid. It is a type of insulin, which is a hormone that regulates the amount of glucose in the blood.
There is no direct evidence suggesting that it affects sleep. However, managing blood sugar levels effectively can help you maintain overall health, which might indirectly impact your sleep quality.
There is no direct evidence to suggest that it affects fertility. However, good diabetes control is essential for reproductive health. If you have concerns about fertility, it is best to discuss this with your doctor.
There are other forms of insulin available, but it is best to consult your doctor before considering a switch as each form of insulin has its unique properties and may not suit everyone’s needs.
It starts working approximately 10-20 minutes after injection. It reaches its peak activity around 1-3 hours after injection and lasts for about 3-5 hours. However, these times may vary among individuals.
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