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Isoflurane

Uses of Isoflurane

  • The primary use of Isoflurane is as a general anaesthetic for inducing and maintaining unconsciousness during major surgical procedures. It falls under the class of halogenated ether anaesthetics.

Side effects of Isoflurane

  • Nausea and vomiting

  • Arrhythmias such as bradycardia or tachycardia

  • Hypotension

  • Respiratory depression

  • Shivering

How Isoflurane works

  • Isoflurane is a halogenated ether anaesthetic. It is believed to work by acting on various molecular targets in the central nervous system, including GABA, glycine, and glutamate receptors, along with two-pore-domain potassium channels. This results in a depression of the central nervous system, leading to loss of consciousness, pain relief, suppression of autonomic reflexes, and relaxation of skeletal muscles.

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 3 years

Bachelor of Dental Surgery

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Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 9 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Isoflurane is available in liquid form and is administered via inhalation using a calibrated vaporizer specifically designed for this purpose. It is essential to remember that only trained anaesthesia personnel should handle and administer Isoflurane.

Age and Dose Restrictions

  • Isoflurane can be used in both adult and paediatric patients. The dosage differs based on the age of the patient, the procedure being carried out, and the patient's response to the anaesthetic.

Contraindications

  • Isoflurane is contraindicated in individuals with a known or suspected genetic susceptibility to malignant hyperthermia or patients with a history of malignant hyperthermia.

Other Medications to Avoid

  • Isoflurane may interact with other CNS depressants (such as estazolam and temazepam), neuromuscular blockers (like rocuronium), beta-blockers (such as atenolol) and opioids (like morphine).

Overdose and Missed Dose

  • Overdose is much less likely as Isoflurane is administered by a doctor during a surgical procedure.

  • As Isoflurane is administered by a doctor during a surgical procedure, the likelihood of missing a dose is extremely low.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor. To manage some of the side effects:

  • Ensure you stay well hydrated to help manage possible nausea and vomiting.

  • Take rest in a dark, quiet room if you experience headaches after the procedure.

Use in Driving and Operating Machinery

  • As Isoflurane is used for general anaesthesia, it is advised to avoid driving or operating heavy machinery until fully recovered from its effects.

Use in Pregnancy and Lactation

  • The use of Isoflurane during pregnancy and lactation should be considered only if your doctor thinks that the potential benefit justifies the potential risk to the baby. It is strongly advised to consult your doctor about its use during these periods.

Caution in Other Conditions

  • Patients with renal or liver impairment should exercise extra caution when administered Isoflurane. It should also be used carefully in patients with respiratory disorders as it can depress respiratory functions.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in proteins, vitamins, and minerals to assist in rapid post-surgical recovery.

  • Once recovered from the anaesthesia effects and surgery, resume light physical activities as recommended by your doctor to promote blood circulation and faster healing.

  • Ensure you get ample rest to allow your body to recover effectively after the surgical procedure.

Frequently asked questions

No, Isoflurane does not cause any dependency or withdrawal symptoms. It is a general anaesthetic used to induce and maintain unconsciousness during surgical procedures.

As a synthetic compound, Isoflurane does not contain any animal-derived ingredients and can be considered vegan-friendly. However, it's always best to consult your doctor for such specifics.

There are no known natural alternatives to Isoflurane. General anaesthetics like Isoflurane have very specific effects that cannot be replicated by natural substances.

Isoflurane is rapidly absorbed via the lungs and around 95% of absorbed Isoflurane is eliminated unchanged via the lungs. Its elimination half-life is around 20-70 minutes after discontinuing anaesthesia.

Isoflurane is not associated with affecting fertility in men or women. If you have concerns about fertility and the use of this medication, consult your doctor for more information.

There is no direct correlation between Isoflurane and sleep or mood. However, after surgery, some patients may experience changes in mood or sleep patterns. This is generally due to the overall stress and recovery from the surgery rather than the effects of Isoflurane.

No, Isoflurane is not a steroid. It is a general anaesthetic used for inducing and maintaining general anaesthesia during major surgical procedures.

Terms & Conditions

Available medicines for ISOFLURANE
Sosrane 100 % Liquid 250 ML
Sosrane 100 % Liquid 250 ML
Neon Laboratories Ltd
Pack of 250 ML
₹1600
MRP ₹2000
20% OFF
Sosrane [isoflurane] 100 % Liquid 100 ML
Sosrane [isoflurane] 100 % Liquid 100 ML
Neon Laboratories Ltd
Pack of 100 ML
₹1800
MRP ₹2250
20% OFF
Isotroy 30 Liquid For Inhalation 30ml
Isotroy 30 Liquid For Inhalation 30ml
Troikaa Pharmaceuticals Ltd
Pack of 30 ML
₹247.07
MRP ₹308.84
20% OFF
Sosrane 100 % Liquid 30 ML
Sosrane 100 % Liquid 30 ML
Neon Laboratories Ltd
Pack of 30 ML
₹234.32
MRP ₹292.9
20% OFF
Forane Liquid 100 ML
Forane Liquid 100 ML
Abbott Healthcare Pvt. Ltd
Pack of 100 ML
₹902
MRP ₹1127.5
20% OFF
Forane Liquid 250 ML
Forane Liquid 250 ML
Abbott Healthcare Pvt. Ltd
Pack of 250 ML
₹2200
MRP ₹2750
20% OFF
Isotroy 100 Liquid 100ml
Isotroy 100 Liquid 100ml
Troikaa Pharmaceuticals Ltd
Pack of 100 ML
₹823.63
MRP ₹1029.54
20% OFF

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