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Isopropamide + Trifluoperazine

Uses of Isopropamide + Trifluoperazine

  • The main use of Isopropamide + Trifluoperazine is to manage gastrointestinal disorders such as Irritable Bowel Syndrome (IBS), Peptic Ulcers, and Gastroesophageal Reflux Disease (GERD). This medication belongs to the group of combination medicines with anticholinergic and antipsychotic properties.

  • It is also useful in managing conditions that cause nausea and vomiting due to its antiemetic.

Side effects of Isopropamide + Trifluoperazine

  • Drowsiness

  • Dizziness

  • Constipation

  • Dry mouth

  • Anxiety

How Isopropamide + Trifluoperazine works

  • Isopropamide + Trifluoperazine is a medication combination used in managing gastrointestinal disorders.

  • Isopropamide belongs to the class of anticholinergic agents. It primarily works by blocking the action of acetylcholine, a neurotransmitter in the body. This results in the relaxation of muscles in the stomach and intestines, helping to reduce spasms and discomfort in these areas.

  • Trifluoperazine is a phenothiazine antipsychotic. It works on dopamine receptors present in the brain and has potent antiemetic properties. This helps suppress feelings of nausea and vomiting by acting on a specific area in the brain known as the chemoreceptor trigger zone (CTZ).

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Isopropamide + Trifluoperazine is available for use as tablets.

  • The tablets are taken orally.

Age and Dose Restrictions

  • This medicine is meant for use by adults.

Contraindications

This medicine is contraindicated in patients with:

  • Known hypersensitivity to Isopropamide, Trifluoperazine, or other Phenothiazines

  • Angle-closure glaucoma

  • Pyloric stenosis

  • Prostatic hypertrophy

  • Severe respiratory depression

  • Blood dyscrasias or bone marrow depression

  • Parkinson's disease

  • Coma or CNS depression

Other Medications to Avoid

  • This combination may interact with anticholinergic medicines (such as atropine), CNS depressants (such as Alcohol, Opioids, Sedatives), antihypertensives (like ace inhibitors and beta blockers), Levodopa and dopamine agonists (including Ropinirole and Pramipexole), lithium (used in bipolar disorder), and antacids (such as Aluminium hydroxide and Magnesium hydroxide).

Overdose and Missed Dose

  • An overdose of Isopropamide + Trifluoperazine may cause severe drowsiness, confusion, agitation, enlarged pupils, dry mouth, flushing of the skin, decreased bowel sounds, urinary retention, rapid heartbeat or irregular heart rhythm. If you experience such symptoms, it is crucial to contact a doctor immediately.

  • If you miss a dose of this medicine, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • To manage dry mouth, sip water regularly or use sugar-free gum to stimulate saliva production.

  • If experiencing constipation, increase intake of dietary fibre and fluids.

Use in Driving and Operating Machinery

  • This medication may impair your ability to drive or operate heavy machinery due to potential side effects like dizziness and drowsiness. Avoid engaging in such activities if these symptoms are present.

Use in Pregnancy and Lactation

  • Isopropamide + Trifluoperazine is classified as pregnancy category C. This means potential risks may exist. It should be used during pregnancy only if clearly needed. It is not recommended during breastfeeding as it can pass into breast milk.

Caution in Other Conditions

Use Isopropamide + Trifluoperazine with caution if you have cardiovascular disease, liver or kidney disease, history of seizures, or diabetes

Special Dietary and Lifestyle Recommendations

If managing conditions like IBS or peptic ulcers with Isopropamide + Trifluoperazine, consider incorporating dietary adjustments:

  • Increase your intake of soluble fibre (such as oats, nuts, and seeds) which can help manage bowel irregularity.

  • Limit foods that are high in fat which can trigger indigestion.

  • Eat smaller, more frequent meals to ease gastrointestinal discomfort.

  • Stay hydrated by drinking plenty of water throughout the day which aids digestion.

  • Maintain a moderate level of activity such as walking or yoga which can enhance gut motility and overall digestive health.

Frequently asked questions

No, Isopropamide + Trifluoperazine is not a steroid. It is a combination of two active ingredients: Isopropamide, an anticholinergic agent and Trifluoperazine, a phenothiazine antipsychotic.

Yes, one of the common side effects of Isopropamide + Trifluoperazine is drowsiness which might affect sleep.

It is always recommended to consult your doctor if you are planning for pregnancy before using this medication.

There are no specific dietary restrictions required while taking Isopropamide + Trifluoperazine.

Yes, it is safe to take Isopropamide + Trifluoperazine daily as per your doctor's recommendation and prescription.

The exact time for Isopropamide + Trifluoperazine to start showing its effect may vary with each individual. Your doctor can provide the best guidance on this.

Your doctor will prescribe you the timings of taking the medicine. Adhere to those timings for the best results.

Terms & Conditions


Available medicines for ISOPROPAMIDE + TRIFLUOPERAZINE
Stelabid 5/1 MG Tablet 10
Stelabid 5/1 MG Tablet 10
Glaxosmithkline Pharmaceuticals Ltd.
Pack of 10 Units
₹28.64
MRP ₹34.93
18.00% OFF
Stelbid 5/2 MG Tablet 10
Stelbid 5/2 MG Tablet 10
Corona
Pack of 10 Units
₹29.59
MRP ₹36.08
18.00% OFF
Spascol 5/1 MG Tablet 10
Spascol 5/1 MG Tablet 10
Vilco Laboratories Pvt. Ltd
Pack of 10 Units
₹18.04
MRP ₹22.00
18.00% OFF
Gastobid Tablet 10
Gastobid Tablet 10
Thrift Pharmaceuticals
Pack of 10 Units
₹17.22
MRP ₹21.00
18.00% OFF
Stelbid 5/1 MG Tablet 10
Stelbid 5/1 MG Tablet 10
Corona
Pack of 10 Units
₹31.50
MRP ₹38.42
18.00% OFF

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