Itopride + Pantoprazole

Dosage Forms Available

• Itopride + Pantoprazole is available in tablet form that is meant for oral administration.

Age and Dose Restrictions

• This combination is meant for use in adults only.

Contraindications

• This combination is contraindicated in individuals with known hypersensitivity to either itopride or pantoprazole.

• It is also contraindicated in patients with severe liver disease or renal impairment.

Other Medications to Avoid

• This combination may interact with medications metabolised by the CYP450 enzyme system (such as warfarin, diazepam, and phenytoin), those that require an acidic environment for absorption (like ketoconazole, itraconazole, and digoxin), and other prokinetic agents (like metoclopramide) or anticholinergic medicines (like glycopyrrolate).

Overdose and Missed Dose

• An overdose can lead to an increase in the severity of side effects such as headache, abdominal pain, diarrhoea, constipation, nausea, dizziness, flatulence, and dry mouth. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of this combination, take it as soon as you remember. However, if it is nearing the time for your next dose, skip the missed dose and continue with your regular dosage schedule. Never double up on a dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For dry mouth, sipping water regularly and maintaining good oral hygiene can be beneficial.

• Increase your intake of fluids to manage constipation and drink plenty of water to avoid dehydration from diarrhoea.

Use in Driving and Operating Machinery

• This combination may cause dizziness in some individuals. If you experience this side effect, avoid driving or operating heavy machinery until you feel capable.

Use in Pregnancy and Lactation

• The safety and efficacy of this combination during pregnancy and lactation have not been established. Consult your doctor before using this combination during these periods.

Caution in Other Conditions

• Individuals with gastric cancer should consult their doctor before taking this combination, as it may mask symptoms.

Special Dietary and Lifestyle Recommendations

• Minimise intake of spicy, fatty, and fried foods that can aggravate gastrointestinal disorders.

• Limit caffeine consumption as it might trigger stomach acid production.

• Smaller, more frequent meals can help reduce incidents of heartburn or bloating associated with gastro-oesophageal reflux disease (GERD) or dyspepsia.