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Itopride + Rabeprazole

Uses of Itopride + Rabeprazole

  • Itopride + Rabeprazole is primarily used for managing GERD and peptic ulcer disease, and belongs to the group of gastrointestinal medicines.

  • Additionally, this medicine may be used to manage other gastrointestinal disorders characterized by impaired motility and excessive acid production, as determined by a doctor.

Side effects of Itopride + Rabeprazole

  • Headache

  • Diarrhoea

  • Nausea

  • Abdominal pain

  • Dizziness

How Itopride + Rabeprazole works

  • Itopride is a prokinetic agent. It enhances the actions of acetylcholine, a chemical messenger, that improves movement in the digestive tract. This leads to quicker emptying of the stomach and reduces reflux, the backflow of stomach acids into the oesophagus.

  • Rabeprazole is a proton pump inhibitor. It acts by blocking an enzyme in the stomach that is responsible for producing acid. By inhibiting this enzyme, Rabeprazole effectively reduces the amount of acid that the stomach generates.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Itopride + Rabeprazole is available in the form of tablets for oral use.

Age and Dose Restrictions

  • This medicine is intended for use in adults only.

Contraindications

  • Itopride + Rabeprazole is contraindicated for individuals with known hypersensitivity to any of its components. It should not be used by individuals with a history of rabeprazole-induced acute interstitial nephritis.

Other Medications to Avoid

  • This combination may interact with anticoagulants (such as heparin and warfarin), immunosuppressants (like tacrolimus and cyclosporine), chemotherapy agents (including azacitidine and methotrexate), and antiretroviral medicines (such as atazanavir and nelfinavir).

Overdose and Missed Dose

  • In case of an overdose, monitoring and supportive treatment is necessary as haemodialysis is not beneficial due to the high protein binding of both itopride and rabeprazole. Symptoms may vary, and immediate medical attention is recommended.

  • If a dose of Itopride + Rabeprazole is missed, it should be taken as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose and resume your normal dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea, consider taking the medication with or shortly after a meal.

  • If experiencing dry mouth, increase your intake of water or use sugar-free gum to stimulate saliva production.

Use in Driving and Operating Machinery

  • Caution is advised while driving or operating heavy machinery if you experience dizziness or drowsiness as side effects of this medication.

Use in Pregnancy and Lactation

  • Itopride + Rabeprazole should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. Consult your doctor before using this medicine during pregnancy or lactation.

Caution in Other Conditions

  • Patients with severe liver impairment should use this medication with caution due to the lack of extensive clinical data on its use in these individuals.

  • Individuals with severe kidney impairment should also be cautious and consult their doctor.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet low in fatty, spicy, and acidic foods to help manage symptoms of gastroesophageal reflux disease (GERD) which Itopride + Rabeprazole is used to manage.

  • Small, frequent meals are preferable over large meals to avoid putting excess pressure on the stomach.

  • Avoiding caffeine, chocolate, mint, and alcohol can also help reduce GERD symptoms.

  • Elevating the head while sleeping can help prevent nighttime symptoms by keeping stomach acid from travelling back into the esophagus.

  • Smoking cessation is strongly advised as smoking can weaken the esophageal sphincter and exacerbate GERD symptoms.

Frequently asked questions

Yes, Itopride + Rabeprazole can be used for the long-term management of GERD. However, the duration of treatment should be determined by your doctor based on your condition and response to therapy.

No specific effects of Itopride + Rabeprazole on appetite have been reported in the research data provided. If you notice any changes in your appetite while taking this medicine, report it to your doctor.

No, there is no evidence to suggest that Itopride + Rabeprazole has addictive properties. However, you should always use this medicine strictly as directed by your doctor.

The research data provided does not indicate that Itopride + Rabeprazole has a direct impact on mood or emotions. If you notice any changes in your mood or emotional state while taking this medicine, report it to your doctor.

Certain natural supplements may interact with medicines. Therefore, before starting any new natural supplement along with Itopride + Rabeprazole, it is recommended to consult your doctor.

Yes, constipation is one of the reported side effects of Itopride + Rabeprazole. If you experience persistent constipation while taking this medicine, consult your doctor for appropriate management.

The safety of Itopride + Rabeprazole during breastfeeding is not clearly established. Therefore, it should be used only if the potential benefit to the mother justifies the potential risk to the infant. Always consult your doctor before taking any medication while breastfeeding.

Terms & Conditions


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