Kanamycin

Dosage Forms Available

• Kanamycin is available as an injectable solution, which is administered either through the intramuscular or intravenous route.
• Additionally, Kanamycin can be taken orally in the form of capsules.

Age and Dose Restrictions

• This medicine is meant for use by both adults and children. However, specific age restrictions may apply, depending on the severity of the infection and the patient's overall health condition.

Contraindications

• This medicine is contraindicated in patients with known allergies to aminoglycosides.
• It is also contraindicated in individuals with severe renal, vestibular and auditory impairment.

Other Medications to Avoid

• Kanamycin may interact with neuromuscular blockers (such as vecuronium and pancuronium), loop diuretics (including furosemide), and certain anaesthetics (like propofol).

Overdose and Missed Dose

• An overdose of Kanamycin may lead to serious complications such as nephrotoxicity (kidney damage) or ototoxicity (hearing loss). Immediate medical attention is necessary if an overdose is suspected.
• If a dose of Kanamycin is missed, it should be taken as soon as possible unless it is nearly time for the next dose. In such cases, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Adjusting the timing of medication may help manage some side effects.
• Ensuring adequate hydration can help reduce the risk of nephrotoxicity.

Use in Driving and Operating Machinery

• Kanamycin may cause dizziness or drowsiness. It is advised to avoid driving or operating heavy machinery if these symptoms are experienced after administration.

Use in Pregnancy and Lactation

• Kanamycin is generally not recommended during pregnancy and breastfeeding due to potential risks to the fetus and infant. Consulting a doctor before using this medication during pregnancy or lactation is crucial.

Caution in Other Conditions

• Patients with existing kidney diseases should use Kanamycin with caution due to its potential nephrotoxic effects.
• Individuals with hearing problems should also be cautious, as Kanamycin can exacerbate ototoxicity.

Special Dietary and Lifestyle Recommendations

• Maintaining adequate hydration is crucial while using Kanamycin to help mitigate potential kidney damage.
• Monitoring salt intake may be advisable, especially for patients prone to oedema or those with hypertension.
• Regular hearing checks could be beneficial for long-term users of Kanamycin to detect any early signs of ototoxicity.
• Engaging in low-impact physical activities like walking or swimming can support overall health without overstraining the body, especially for those managing severe infections.