Ketorolac Tromethamine

Dosage Forms Available

• Ketorolac Tromethamine is available for use orally (tablet), topically (eye drops), and through intramuscular or intravenous routes (injection).

Age and Dose Restrictions

• This medicine is meant for use in adults only.

Contraindications

• Ketorolac Tromethamine is contraindicated in patients with known allergies to ketorolac or other non-steroidal anti-inflammatory medicines.

• It is also contraindicated in patients with active peptic ulcer disease, gastrointestinal bleeding, advanced renal impairment, and those at risk of renal failure due to volume depletion.

• Other contraindications include patients with suspected or confirmed cerebrovascular bleeding, haemorrhagic diathesis, and those undergoing labour and delivery.

Other Medications to Avoid

• This medicine may interact with other non-steroidal anti-inflammatory medicines (such as ibuprofen and naproxen), anticoagulants (like warfarin and heparin), thrombolytics (such as alteplase), selective serotonin reuptake inhibitors (including fluoxetine and sertraline), lithium, methotrexate, diuretics (such as furosemide), angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (like lisinopril/losartan), and pentoxifylline.

Overdose and Missed Dose

• An overdose of Ketorolac Tromethamine may result in severe gastrointestinal bleeding, renal dysfunction, respiratory depression, and coma. Immediate medical intervention is critical in managing overdose symptoms.

• For eye drops, in case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

• If you miss a dose of Ketorolac Tromethamine, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For gastrointestinal discomfort, consider taking the medication with food or milk.

• Take the medicine close to bedtime to sleep offside effects like headaches and blurred vision. Do this only after consulting your doctor.

Use in Driving and Operating Machinery

• Ketorolac Tromethamine may impair your ability to drive or operate heavy machinery. Avoid these activities if you experience dizziness or drowsiness after taking this medication.

Use in Pregnancy and Lactation

• Ketorolac Tromethamine is not advised during pregnancy, especially in the third trimester due to potential harm to the fetus and adverse effects on labor and delivery.

• It is also not recommended during breastfeeding. Consult your doctor before using this medication if you are pregnant or nursing.

Caution in Other Conditions

• Patients with cardiovascular disease or a history of ulcers or gastrointestinal bleeding should use Ketorolac Tromethamine with extreme caution.

• Caution is also advised for elderly patients and those with hepatic impairment.

Special Dietary and Lifestyle Recommendations

• To manage conditions like acute severe pain for which Ketorolac Tromethamine is prescribed, maintaining a balanced diet rich in fruits, vegetables, whole grains, and lean proteins can help promote overall health.

• Adequate hydration is crucial; strive to drink at least eight glasses of water daily.

• Minimizing alcohol consumption can also be beneficial as it can exacerbate gastrointestinal side effects commonly associated with non-steroidal anti-inflammatory medicines.

• Engage in light to moderate physical activity as tolerated to maintain mobility and overall well-being; however, always consult a doctor before starting any new exercise regimen, especially following surgery or acute injury where Ketorolac Tromethamine might be prescribed.