The primary use of Lithium is in managing bipolar disorder. It is a key medication used to stabilise mood, reducing the severity and frequency of mania episodes and helping to prevent or lessen the intensity of depressive episodes. It is a psychiatric medication.
Lithium may also be used as an adjunct to antidepressants for treatment-resistant depression. In some cases, it may be used off-label for managing other psychiatric conditions such as schizoaffective disorder, aggressive behaviour, and cluster headaches.
Nausea and vomiting
Tremors
Drowsiness and dizziness
Hypothyroidism
Memory impairment
Lithium is a psychiatric medication primarily used as a mood stabiliser. It works by modulating neurotransmitter activity in the brain, specifically enhancing the synthesis of serotonin and increasing gamma-aminobutyric acid (GABA) activity.
Doctor of Medicine
BMS, FMC, MD Resident
Lithium is available in different forms for oral administration. These include immediate-release tablets, extended-release tablets, capsules, and oral solutions.
Lithium is mainly prescribed for adults. It can also be given to children, particularly those above 12 years of age.
Lithium is contraindicated in patients with known allergies to any of its constituents. It is also contraindicated in patients with significant renal dysfunction, severe cardiovascular disease, severe debilitation or dehydration, sodium depletion, and concurrent infection with febrile illnesses.
Lithium can interact with NSAIDs (such as ibuprofen and diclofenac), angiotensin-converting enzyme (ACE) inhibitors (such as lisinopril and enalapril) and certain antipsychotics (like clozapine and olanzapine).
Overdose of Lithium can lead to severe toxicity symptoms such as tremors, ataxia, confusion, seizures, and cardiovascular collapse. If you suspect an overdose, seek immediate medical attention.
If you miss a dose of Lithium, take it as soon as you remember unless it's close to the time of your next scheduled dose. In the latter case, skip the missed dose and continue your regular schedule. Do not double up on doses to compensate for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
For gastrointestinal issues, take the medication with meals or milk to reduce nausea and discomfort.
For excessive thirst and urination, ensure you stay well-hydrated but avoid overhydration.
Lithium may impair your ability to drive or operate heavy machinery, particularly if you experience side effects like dizziness or drowsiness. Avoid these activities if you do not feel alert or coordinated.
The use of Lithium during pregnancy and breastfeeding should be carefully considered due to potential risks. Always consult your doctor before using this medication if you are pregnant or nursing.
Caution is advised when using Lithium in patients with thyroid disease, as Lithium can affect thyroid function. Patients with psoriasis should also exercise caution, as Lithium may exacerbate this skin condition.
Ensure a consistent intake of sodium while taking Lithium, as significant changes can affect Lithium levels in your body.
Stay well-hydrated, especially during hot weather and while exercising.
Frequently asked questions
Yes, Lithium is a naturally occurring alkali metal. It is used in various forms, including as a psychiatric medication.
No, Lithium is not a steroid. It is an alkali metal that is used as a mood stabilizer in psychiatry.
Lithium can potentially affect your sleep. Some people may experience changes in their sleep patterns or have vivid dreams while taking this medication.
Lithium does not typically affect fertility. However, if you are planning to conceive, it is important to talk to your doctor, as it can potentially harm the unborn baby.
Yes, it is safe to take Lithium daily if prescribed by your doctor.
Yes, Lithium is a prescription medicine and should only be taken under the supervision of a qualified doctor.
Therapeutic effects of Lithium may be observed within 1-3 weeks, but full stabilization of mood can take several months.
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