Meropenem + Sulbactam

Dosage Forms Available

• Meropenem + Sulbactam is available for use via the parenteral route (injection).

Age and Dose Restrictions

• This medication is meant for adults and children 3 months of age and older. For paediatric population, dose adjustment is considered based on the child's weight.

Contraindications

• Meropenem + Sulbactam is contraindicated in patients with known hypersensitivity to the components of this medication, namely carbapenems, penicillin's, cephalosporins, or beta-lactamase inhibitors.

Other Medications to Avoid

• This combination may interact with anticonvulsants (such as valproic acid and divalproex sodium), and with renal excretion aiding compounds (like probenecid).

Overdose and Missed Dose

• An overdose of Meropenem + Sulbactam could potentially lead to symptoms such as seizures, confusion and involuntary eye movements. If you suspect an overdose, contact your doctor immediately.

• If you miss a dose of this medication, administer it as soon as you remember. However, if it is close to the time of your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage common side effects such as diarrhoea, nausea, or vomiting, try taking the medication with food.

• For managing headaches or dizziness, ensure that you are well hydrated and rest adequately.

Use in Driving and Operating Machinery

• Meropenem + Sulbactam may cause side effects such as dizziness or drowsiness, which could affect your ability to drive or operate heavy machinery. It is advised to refrain from such activities until you know how this medication affects you.

Use in Pregnancy and Lactation

• Meropenem + Sulbactam should be used during pregnancy and lactation only if the benefits to the mother outweigh the potential risks to the foetus or infant. Always consult your doctor before using this medicine in pregnancy and breastfeeding.

Caution in Other Conditions

• Patients with renal impairment should exercise caution when taking Meropenem + Sulbactam as dose adjustments may be necessary based on creatinine clearance rates.

• Similarly, patients with a history of seizures or CNS disorders should be closely monitored while on this medication.

Special Dietary and Lifestyle Recommendations

• Maintain good hydration throughout treatment to support kidney function, as this medication is primarily eliminated via renal excretion.

• Good personal hygiene practices are vital when dealing with bacterial infections.