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Metadoxine

Uses of Metadoxine

  • The primary use of Metadoxine is in the management of acute and chronic alcohol intoxication and it belongs to the group of detoxification agents.

  • It is also used as a supportive medication in treating alcohol dependence, reducing alcohol withdrawal symptoms and managing fatty liver disease caused by alcoholism.

Side effects of Metadoxine

  • Nausea and vomiting

  • Headache and dizziness

  • Fatigue

  • Skin rash and itching

How Metadoxine works

  • Metadoxine is an alcohol intoxication and dependence management medicine. It is an ionic salt, consisting of two components - pyridoxine (Vitamin B6) and pidolic acid (pyrrolidone carboxylate). As an antioxidant, Metadoxine likely protects the liver from the damage caused by alcohol and its metabolites.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Metadoxine is available in the form of tablets for oral administration.

  • This medicine is also administered as an intramuscular or intravenous injection, especially in cases of acute alcohol intoxication.

Age and Dose Restrictions

  • Metadoxine is meant for use in adults, and children over the age of 12.

Contraindications

  • Metadoxine is contraindicated in patients who have known allergies to pyridoxine or pidolic acid.

  • This medicine should not be used in patients with severe liver impairment, due to its potential impact on liver function.

Other Medications to Avoid

  • Metadoxine may interact with sedative agents (such as benzodiazepines) and opioids (such as morphine, methadone and oxycodone).

Overdose and Missed Dose

  • Overdosing on Metadoxine can lead to unpleasant symptoms such as nausea, vomiting, and abdominal pain. If you suspect an overdose, seek immediate medical attention.

  • In case you miss a dose of Metadoxine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For mild nausea or vomiting, try taking your medicine with a light snack or meal.

  • If you experience drowsiness or dizziness after taking Metadoxine, ensure that you are well-rested before undertaking activities that require concentration.

Use in Driving and Operating Machinery

  • Metadoxine may cause dizziness or drowsiness. If you experience these side effects, it is advised to avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • The use of Metadoxine during pregnancy and lactation should only be considered if the potential benefits outweigh the risks. It is crucial to consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients with kidney disease should exercise caution while taking Metadoxine, as dose adjustments may be required.

Special Dietary and Lifestyle Recommendations

  • Regular check-ups can aid in monitoring liver health, especially for those taking Metadoxine for an extended duration.

Frequently asked questions

No, Metadoxine is not a steroid. It is primarily a medicine used to manage alcohol intoxication and alcohol dependence.

Metadoxine is not associated with any direct effects on sleep. It is primarily used to treat alcohol intoxication and liver conditions, with no known impact on sleep patterns.

Metadoxine is not associated with effects on fertility. It is mainly used for managing alcohol-related conditions and liver health, with no known impact on reproductive health.

Metadoxine appears to be well tolerated with few serious adverse effects. However, the safety of long-term use beyond a few months is not well studied. You should only use Metadoxine as directed by your doctor.

Metadoxine starts reducing blood alcohol levels and improving symptoms within a few hours of first dose administration.

There are no specific guidelines on the best time to take Metadoxine. For specific guidelines on the best time to take Metadoxine, consult your doctor.

Yes, Metadoxine may cause allergic reactions such as skin rashes, itching or shortness of breath. If you experience these symptoms, stop taking the medication immediately and consult your doctor.

Terms & Conditions


Available medicines for METADOXINE
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Metadoxil 60 MG Injection 5 ML
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Viboliv 300 MG Injection 5 ML
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Metadoxil 500 MG Tablet 10
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