Metformin + Methylcobalamin

Dosage Forms Available

• Metformin + Methylcobalamin is available in the form of tablets intended to be consumed orally.

Age and Dose Restrictions

• Metformin + Methylcobalamin is primarily intended for use in adults.

• It may be prescribed to adolescents and children over the age of 10, under the careful supervision of a doctor.

Contraindications

• This combination medicine is contraindicated in individuals with known hypersensitivity to either Metformin or Methylcobalamin.

• It is not recommended for patients with severe renal impairment or metabolic acidosis, including diabetic ketoacidosis.

Other Medications to Avoid

• Metformin + Methylcobalamin may interact with cationic medicines (e.g., amiloride, digoxin, morphine, ranitidine, trimethoprim, and vancomycin), carbonic anhydrase inhibitors (e.g., topiramate, zonisamide, acetazolamide) and other heart medicines (e.g., ranolazine, dolutegravir) and H2 blockers (e.g., cimetidine).

Overdose and Missed Dose

• An overdose of Metformin + Methylcobalamin could lead to symptoms of lactic acidosis. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage gastrointestinal side effects like nausea or upset stomach, take the medicine with or immediately after a meal.

• Drinking plenty of water can help manage side effects like headaches and fatigue.

Use in Driving and Operating Machinery

• Metformin + Methylcobalamin may cause dizziness or fatigue in some people. If you experience these side effects, avoid driving or operating heavy machinery until you feel better.

Use in Pregnancy and Lactation

• It is recommended to consult your doctor before taking Metformin + Methylcobalamin during pregnancy or while breastfeeding.

Caution in Other Conditions

• Individuals with severe kidney problems or metabolic acidosis should be cautious when taking Metformin + Methylcobalamin.

• Elderly patients and those undergoing radiologic procedures with intravascular iodinated contrast materials should also exercise caution.

Special Dietary and Lifestyle Recommendations

• Avoid excessive intake of alcohol as it may increase the risk of lactic acidosis with Metformin.

• Regular monitoring of blood glucose levels is recommended.