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Metformin + Methylcobalamin

Uses of Metformin + Methylcobalamin

  • Metformin + Methylcobalamin is primarily used to help control high blood sugar in patients with type 2 diabetes and is a part of the biguanide class of antidiabetic agents.

  • Additionally, it assists in preventing complications of diabetes such as kidney damage, blindness, nerve problems, limb amputations, and sexual function issues. Methylcobalamin on its own is used to treat and prevent vitamin B12 deficiency anemia and may also be used to treat diabetic neuropathy.

Side effects of Metformin + Methylcobalamin

  • Nausea

  • Vomiting

  • Stomach upset

  • Diarrhoea

  • Weakness

  • Fatigue

How Metformin + Methylcobalamin works

  • Metformin + Methylcobalamin is a combination medicine used for managing blood glucose levels in type 2 diabetes.

  • Metformin, a biguanide antidiabetic agent, works by reducing the amount of glucose produced by the liver, decreasing intestinal absorption of glucose, and improving insulin sensitivity. This means that it helps your body to use insulin more efficiently and effectively, without causing low blood sugar or 'hypoglycaemia'.

  • Methylcobalamin is the activated form of Vitamin B12. It serves many roles in the body including supporting brain function and the formation of red blood cells. It is involved in DNA synthesis, fatty acid synthesis, and energy production.

  • Together, these two components work in harmony to improve blood sugar control in people with type 2 diabetes. They help to prevent long-term complications associated with diabetes such as kidney damage, blindness, nerve problems, and heart disease.

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Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Ashmita Borgohain
Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Expert Advice

Dosage Forms Available

  • Metformin + Methylcobalamin is available in the form of tablets intended to be consumed orally.

Age and Dose Restrictions

  • Metformin + Methylcobalamin is primarily intended for use in adults.

  • It may be prescribed to adolescents and children over the age of 10, under the careful supervision of a doctor.

Contraindications

  • This combination medicine is contraindicated in individuals with known hypersensitivity to either Metformin or Methylcobalamin.

  • It is not recommended for patients with severe renal impairment or metabolic acidosis, including diabetic ketoacidosis.

Other Medications to Avoid

  • Metformin + Methylcobalamin may interact with cationic medicines (e.g., amiloride, digoxin, morphine, ranitidine, trimethoprim, and vancomycin), carbonic anhydrase inhibitors (e.g., topiramate, zonisamide, acetazolamide) and other heart medicines (e.g., ranolazine, dolutegravir) and H2 blockers (e.g., cimetidine).

Overdose and Missed Dose

  • An overdose of Metformin + Methylcobalamin could lead to symptoms of lactic acidosis. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage gastrointestinal side effects like nausea or upset stomach, take the medicine with or immediately after a meal.

  • Drinking plenty of water can help manage side effects like headaches and fatigue.

Use in Driving and Operating Machinery

  • Metformin + Methylcobalamin may cause dizziness or fatigue in some people. If you experience these side effects, avoid driving or operating heavy machinery until you feel better.

Use in Pregnancy and Lactation

  • It is recommended to consult your doctor before taking Metformin + Methylcobalamin during pregnancy or while breastfeeding.

Caution in Other Conditions

  • Individuals with severe kidney problems or metabolic acidosis should be cautious when taking Metformin + Methylcobalamin.

  • Elderly patients and those undergoing radiologic procedures with intravascular iodinated contrast materials should also exercise caution.

Special Dietary and Lifestyle Recommendations

  • Avoid excessive intake of alcohol as it may increase the risk of lactic acidosis with Metformin.

  • Regular monitoring of blood glucose levels is recommended.

Frequently asked questions

No, Metformin + Methylcobalamin is not a steroid. It is a combination of an antidiabetic agent and an activated form of vitamin B12.

No direct link has been established between Metformin + Methylcobalamin and sleep patterns. However, if you feel that your sleep is disturbed after starting this medicine, it is recommended to consult your doctor.

No, there is no evidence to suggest that Metformin + Methylcobalamin has any significant effects on fertility. However, if you are planning to conceive, it is advisable to consult with your doctor.

While diet restrictions are not specifically related to this medication, maintaining a balanced diet is crucial when managing diabetes. Also, excessive intake of alcohol should be avoided as it may increase the risk of lactic acidosis.

Metformin + Methylcobalamin is generally safe for daily use when taken as prescribed by your doctor. It is intended for long-term treatment of type 2 diabetes.

The time for this medicine to show its effect may vary from person to person, but generally, some improvement in blood glucose levels can be seen within a week or two.

It is usually recommended to take Metformin + Methylcobalamin as prescribed by your doctor. This will be based on your individual treatment plan and dietary habits.

Terms & Conditions


Metformin + Methylcobalamin in other salts

ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE) + VITAMIN D3 (CHOLECALCIFEROL)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEASCORBIC ACID + BIOTIN + CALCIUM PANTOTHENATE + FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + RIBOFLAVIN + THIAMINE MONONITRATE + ZINC SULPHATEELEMENTAL CALCIUM + L-METHYLFOLATE CALCIUM + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATE + VITAMIN D3 (CHOLECALCIFEROL)METHYLCOBALAMIN + PREGABALINDAPAGLIFLOZIN + METFORMINGLICLAZIDE + METFORMINGLIMEPIRIDE + METFORMINGLIMEPIRIDE + METFORMIN + PIOGLITAZONEGLIMEPIRIDE + METFORMIN + VOGLIBOSELINAGLIPTIN + METFORMINMETFORMINMETFORMIN + SITAGLIPTINMETFORMIN + VILDAGLIPTINMETFORMIN + VOGLIBOSEMETHYLCOBALAMINMETFORMIN + TENELIGLIPTINL METHYL FOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEPREGABALIN + NORTRIPTYLINE + METHYLCOBALAMINGABAPENTIN + METHYLCOBALAMINL METHYLFOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEDOCOSAHEXAENOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEMETFORMIN + MYO INOSITOLALPHA LIPOIC ACID + BENFOTIAMINE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)DULOXETINE + METHYLCOBALAMINALPHA LIPOIC ACID + BENFOTIAMINE + ELEMENTAL CHROMIUM + INOSITOL + METHYLCOBALAMINDOCOSAHEXAENOIC ACID + L METHYLFOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEALPHA LIPOIC ACID + METHYLCOBALAMIN + PREGABALINALPHA LIPOIC ACID + GABAPENTIN + METHYLCOBALAMINALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + THIAMINE MONONITRATE + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + METHYLCOBALAMINALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + ELEMENTAL CHROMIUM + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + CHROMIUM PICOLINATE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + SELENOMETHIONINE + ZINC MONOMETHIONINEALPHA LIPOIC ACID + BENFOTIAMINE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINE + VITAMIN D3 (CHOLECALCIFEROL)ALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + CHROMIUM PICOLINATE + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 (PYRIDOXINE)ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACID + METHYLCOBALAMINBENFOTIAMINE + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PYRIDOXINE HYDROCHLORIDE + VITAMIN D3 (CHOLECALCIFEROL)METHYLCOBALAMIN + NICOTINAMIDE + VITAMIN B6 / PYRIDOXINED-PANTHENOL + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDEMETHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEMETHYLCOBALAMIN + NICOTINAMIDE + VITAMIN B6 (PYRIDOXINE)D-PANTHENOL + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 (PYRIDOXINE)FERROUS ASCORBATE + FOLIC ACID + METHYLCOBALAMINEPALRESTAT + METHYLCOBALAMINMETFORMIN + PIOGLITAZONEAMITRIPTYLINE + METHYLCOBALAMINGLIBENCLAMIDE + METFORMINGLIPIZIDE + METFORMINFOLIC ACID + L-CARNITINE / LEVOCARNITINE + METHYLCOBALAMINALPHA LIPOIC ACID + METFORMINCALCIUM-5 METHYLTETRAHYDROFOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEGLICLAZIDE + METFORMIN + PIOGLITAZONEMETFORMIN + PIOGLITAZONE + VOGLIBOSEGLIBENCLAMIDE + METFORMIN + PIOGLITAZONEGLIBENCLAMIDE + METFORMIN + ROSIGLITAZONEACARBOSE + METFORMINATORVASTATIN + GLIMEPIRIDE + METFORMINMETFORMIN + ROSIGLITAZONEMETFORMIN + REPAGLINIDED CHIRO INOSITOL + L-METHYLFOLATE + METFORMIN + METHYLCOBALAMIN + MYO INOSITOLEMPAGLIFLOZIN + METFORMINATORVASTATIN + METFORMINFOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 / PYRIDOXINEGLIMEPIRIDE + METFORMIN + ROSIGLITAZONEALOGLIPTIN + METFORMINDIACEREIN + GLUCOSAMINE SULFATE POTASSIUM CHLORIDE + METHYL SULFONYL METHANE + METHYLCOBALAMINDAPAGLIFLOZIN + METFORMIN + SITAGLIPTINDAPAGLIFLOZIN + METFORMIN + VILDAGLIPTINGLIMEPIRIDE + METFORMIN + SITAGLIPTINDAPAGLIFLOZIN + GLIMEPIRIDE + METFORMINMETFORMIN + PIOGLITAZONE + SITAGLIPTIN
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