Metformin + Remogliflozin Etabonate
Uses of Metformin + Remogliflozin Etabonate
- The primary use of Metformin + Remogliflozin Etabonate is to manage the condition of type 2 diabetes mellitus in adults. This medication falls under the class of antidiabetic medicines.
Side effects of Metformin + Remogliflozin Etabonate
Urinary tract infections
Low blood sugar (hypoglycemia)
Increased urination
Genital mycotic infections
Nausea
How Metformin + Remogliflozin Etabonate works
Metformin + Remogliflozin Etabonate is an antidiabetic combination.
Metformin is a biguanide. It works by reducing the production of glucose in your liver, slowing down glucose absorption from your intestines, and improving your body's sensitivity to insulin. These actions help to decrease the amount of sugar in your blood.
Remogliflozin Etabonate is an SGLT2 inhibitor. It operates by blocking the sodium-glucose co-transporter 2 (SGLT2) in your kidneys, which normally reabsorbs glucose back into your blood. By inhibiting this co-transporter, more glucose is excreted through your urine, thereby reducing the amount of sugar in your blood.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
- Metformin + Remogliflozin Etabonate is available for use via the oral route in the form of tablets.
Age and Dose Restrictions
- This combination medicine is intended for use in adults only.
Contraindications
- Metformin + Remogliflozin Etabonate is contraindicated in patients with type 1 diabetes mellitus, diabetic ketoacidosis, severe kidney impairment, end-stage renal disease, patients on dialysis, known hypersensitivity to either Metformin or Remogliflozin Etabonate, and acute or chronic metabolic acidosis including lactic acidosis.
Other Medications to Avoid
- This combination may interact with carbonic anhydrase inhibitors (such as topiramate, zonisamide, acetazolamide), cationic medicines that are eliminated by renal tubular secretion (like amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, or vancomycin), and diuretics.
- It is crucial to inform your doctor about all the medicines you are currently taking to check for potential interactions.
Overdose and Missed Dose
- An overdose of this medication may lead to lactic acidosis and should be managed with supportive measures as directed by your doctor.
- If you miss a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and follow the usual dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.
- Drinking plenty of fluids can help manage increased urination due to Remogliflozin Etabonate.
- Having small, frequent meals can help manage nausea, diarrhoea, and abdominal discomfort due to Metformin.
Use in Driving and Operating Machinery
- This combination may cause dizziness. Hence, caution should be exercised when driving or operating heavy machinery.
Use in Pregnancy and Lactation
- It is advisable to consult your doctor before using Metformin + Remogliflozin Etabonate during pregnancy and breastfeeding.
Caution in Other Conditions
- Caution should be used in patients with severe renal impairment, end-stage renal disease, patients on dialysis, acute or chronic metabolic acidosis including lactic acidosis.
Special Dietary and Lifestyle Recommendations
- A healthy diet low in sugar and saturated fats may help improve the effectiveness of this medication in managing type 2 diabetes.
- Regular physical activity can also contribute to better blood sugar control.
- It is beneficial to keep regular monitoring of your blood sugar levels.
- Refrain from excessive alcohol intake as it increases your risk of lactic acidosis while on this medication.
Frequently asked questions
How does Metformin + Remogliflozin Etabonate manage type 2 diabetes mellitus?
Metformin + Remogliflozin Etabonate is a combination of two antidiabetic medicines which work together to control blood glucose levels in the body. Metformin reduces glucose production in the liver and increases the body's sensitivity to insulin, while Remogliflozin Etabonate inhibits glucose reabsorption in the kidneys.
Can I take Metformin + Remogliflozin Etabonate if I have type 1 diabetes?
No, Metformin + Remogliflozin Etabonate is not recommended for patients with type 1 diabetes. It is only used to manage type 2 diabetes.
Are there any conditions where I cannot take Metformin + Remogliflozin Etabonate?
Yes, this medicine should not be taken by patients with severe kidney impairment or end-stage renal disease, acute or chronic metabolic acidosis, including lactic acidosis, or those with known hypersensitivity to either Metformin or Remogliflozin Etabonate.
What are the potential side effects of taking Metformin + Remogliflozin Etabonate?
Some common side effects include genital mycotic infections, urinary tract infections, hypoglycemia (low blood sugar), nausea, and increased urination.
Can Metformin + Remogliflozin Etabonate interact with other medicines?
Yes, it can interact with several other medicines. It is important to inform your doctor about all the medications you are taking to check for potential interactions.
Is it safe to take Metformin + Remogliflozin Etabonate during pregnancy?
The use of Metformin + Remogliflozin Etabonate during pregnancy should only be considered if the potential benefit justifies the possible risk to the foetus. Always consult your doctor for individual advice.
Can I take Metformin + Remogliflozin Etabonate if I have liver impairment?
Metformin + Remogliflozin Etabonate is not recommended for patients with hepatic impairment. Consult your doctor for more information.
Metformin + Remogliflozin Etabonate in other salts
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