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Metformin + Vildagliptin

ANTIDIABETIC

Uses of Metformin + Vildagliptin

  • Metformin + vildagliptin is used in the management of type 2 diabetes mellitus when either metformin or vildagliptin treatment is inadequate. 
  • This combination is also used with other antidiabetics when diet and exercise to improve glycaemic control.

Side effects of Metformin + Vildagliptin

  • Hypoglycemia 
  • Dizziness
  • Headache
  • Nausea

How Metformin + Vildagliptin works

  • Metformin + Vildagliptin is an oral antihyperglycemic agent.
  • Metformin is a biguanide. It acts by reducing glucose production in the liver and improving insulin sensitivity.
  • Vildagliptin is a dipeptidyl peptidase-4 (OPP-4) inhibitor. It enhances insulin secretion and reduces glucagon levels, improving blood glucose regulation. 

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Metformin + Vildagliptin can be combined orally (tablet).

Age And Dose Restrictions 

  • This combination is not intended to be used by children below 18 years. 

Contraindications 

  • This combination is contraindicated in patients with a history of hypersensitivity to metformin or vildagliptin.

Other Medications To Avoid With This Medicine

  • Avoid taking antifungals (ketoconazole), antidepressants (fluoxetine), antihypertensives (amlodipine), diuretics (furosemide), thyroid medications (levothyroxine), corticosteroids (prednisolone), phenothiazines (serentil), estrogens (estradiol), oral contraceptives (norethindrone), anticonvulsants (phenytoin), and antiepileptics (ranolazine). These medications may alter the safety and effectiveness of Metformin + Vildagliptin.

Overdose And Missed Dose

  • Overdose can cause lactic acidosis. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of this combination, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • To manage hypoglycemia (low blod sugar), eat or drink a source of sugar such as fruit juice, candy, crackers, raisins, or non-diet soda. Once your blood sugar stabilises, have a balanced snack or meal to prevent another drop. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

  • This combination can make you feel dizzy. It is not recommended to drive, operate machinery, or do other activities that require mental alertness or coordination till you know how the combination affects you.

Use In Pregnancy And Lactation

  • This combination is not recommended during pregnancy and breastfeeding.

Caution In Other Conditions

  • Caution is advised in older adults and patients with diabetic ketoacidosis, pancreatitis, joint pain, irregular heartbeat, hypoglycaemia (low blood sugar), vitamin B12 deficiency and kidney and liver impairment.

Special Dietary And Lifestyle Recommendation

  • Incorporate foods with low glycemic index, such as green leafy vegetables, whole grains, berries, citrus fruits, chia seeds, bitter gourd and extra virgin olive oil.
  • Engage in regular physical activity, which can help improve insulin sensitivity and blood sugar control.
  • Watch your sodium intake and not exceed 5 gm daily to avoid heart conditions with diabetes.
  • Monitor your blood sugar levels regularly and stay connected with your doctor to adjust your treatment plan.

Frequently asked questions

This combination typically shows its effect within a few hours after ingestion. However, individual responses may vary. 

This combination is not habit-forming and is generally safe when used as directed.

The use of this combination is not known to impair female fertility.

This combination usually requires a prescription and is not available over the counter.

This combination is generally considered safe when used as prescribed and monitored by a doctor. However, individuals with diabetic ketoacidosis, pancreatitis, joint pain, irregular heartbeat, and hypoglycaemia (low blood sugar) should consult a doctor before taking this tablet.

This combination may cause constipation as an uncommon side effect. However, individual responses may vary. If you have persistent constipation while taking this combination, consult your doctor.

This combination is not recommended to manage type 1 diabetes. It is used only for type 2 diabetes.

Terms & Conditions


Available medicines for METFORMIN + VILDAGLIPTIN
Zomelis Met 50mg/500mg Tablet 15
Zomelis Met 50mg/500mg Tablet 15
Eris Lifesciences Ltd
Pack of 15 Units
₹147.34
MRP ₹179.68
18.00% OFF
Jalra M 50mg/500mg Tablet 15
Jalra M 50mg/500mg Tablet 15
Usv Pvt Ltd
Pack of 15 Units
₹266.50
MRP ₹325.00
18.00% OFF
Gliptagreat M 500 Tablet 10
Gliptagreat M 500 Tablet 10
Mankind Pharmaceuticals Ltd.
Pack of 10 Units
₹66.93
MRP ₹81.62
18.00% OFF
Vildader Met 50mg/500mg Tablet 15
Vildader Met 50mg/500mg Tablet 15
Elder Prroject Limited
Pack of 15 Units
₹104.29
MRP ₹209.00
50.10% OFF
Cipvildin M 50mg/1000mg Tablet 15
Cipvildin M 50mg/1000mg Tablet 15
Cipla Ltd.
Pack of 15 Units
₹82.33
MRP ₹165.00
50.10% OFF
Galvus Met 50mg/500mg Tablet 15
Galvus Met 50mg/500mg Tablet 15
Cipla Ltd.
Pack of 15 Units
₹296.16
MRP ₹361.17
18.00% OFF
Vildamac M 50/500 Tablet 15
Vildamac M 50/500 Tablet 15
Macleods Pharmaceuticals Pvt.ltd
Pack of 15 Units
₹135.30
MRP ₹165.00
18.00% OFF
Cipvildin M 50mg/500mg Tablet 15
Cipvildin M 50mg/500mg Tablet 15
Cipla Ltd.
Pack of 15 Units
₹78.22
MRP ₹156.75
50.10% OFF

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