Methylcobalamin + Niacinamide + Vitamin B6 / Pyridoxine

Dosage Forms Available

• Methylcobalamin + Niacinamide + Vitamin B6 / Pyridoxine is available for oral administration in the form of tablets, capsules and sublingual tablets designed to dissolve under the tongue for faster absorption.

• Additionally, there are injectable forms of this combination, meant to be administered intramuscularly by a healthcare professional.

Age and Dose Restrictions

• Methylcobalamin + Niacinamide + Vitamin B6 (Pyridoxine) supplements are generally used in both adults and children. However, the dosage and form may vary based on age and specific health needs.Consultation with doctor is recommended for dose advise.

Contraindications

• This combination is contraindicated in patients with known allergies to any of the active ingredients.

• It is also contraindicated in patients with megaloblastic anaemia due to folate deficiency and those with Leber's hereditary optic neuropathy.

Other Medications to Avoid

• Methylcobalamin + Niacinamide + Vitamin B6 / Pyridoxine may interact with anticonvulsants (such as phenytoin and carbamazepine), chemotherapy agents (like cisplatin and 5-fluorouracil), diabetes medication (like metformin), antacids (like omeprazole and cimetidine), and certain Parkinson's disease medications (like levodopa and carbidopa).

Overdose and Missed Dose

• If you accidentally take more than the recommended dose of this medicine, contact your doctor immediately. Overdosing may result in symptoms like severe skin reactions, upset stomach or nerve effects.

• In case you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage gastrointestinal side effects like upset stomach, nausea and diarrhoea.

• If you experience skin reactions like itching or rash, avoid itching the area and keep it clean.

Use in Driving and Operating Machinery

• This combination may cause dizziness or headache in some people. Therefore, avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• Use of Methylcobalamin + Niacinamide + Vitamin B6 / Pyridoxine in pregnancy and during lactation should be done under medical advice. Consult your doctor before using this combination if you are pregnant or breastfeeding.

Caution in Other Conditions

• This combination should be used with caution in patients with kidney disease, as high doses of Vitamin B6 can cause neurological disorders.

• Patients with a history of gout or peptic ulcers should also exercise caution while taking this medication.

Special Dietary and Lifestyle Recommendations

• To prevent vitamin B deficiencies, ensure a diet rich in whole grains, lean proteins, fruits, vegetables, dairy products and fortified cereals.

• Regular physical activity helps improve overall health and boosts immune system functioning.