Metoclopramide + Paracetamol/acetaminophen

Dosage Forms Available

• Metoclopramide + Paracetamol/Acetaminophen is available as an oral tablet formulation.

Age and Dose Restrictions

• Metoclopramide + Paracetamol/Acetaminophen is meant for use in adults and not recommended for use in children below 18 years.

Contraindications

• Metoclopramide + Paracetamol/Acetaminophen is contraindicated in patients with known hypersensitivity to either of the components, in those with gastrointestinal haemorrhage or obstruction or perforation, in those with pheochromocytoma (a rare tumour of the adrenal gland) or epilepsy, with Parkinson's disease, and with severe liver or kidney impairment.

Other Medications to Avoid

• Metoclopramide + Paracetamol/Acetaminophen may interact with anticholinergic medications (e.g., dicyclomine and propantheline), medications that delay gastric emptying like opioids (e.g., tramadol), antocoagulants (e.g., warfarin), anticonvulsants (e.g., carbamazepine, hydantoins), antibiotics (e.g., isoniazid, or platelet inhibitory agents (e.g., sulfinpyrazone).

Overdose and Missed Dose

• Excessive intake of Metoclopramide + Paracetamol/Acetaminophen may intensify adverse effects such as extrapyramidal reactions (involuntary, uncontrollable movements), drowsiness, disorientation, and seizures. In case of an overdose, immediate medical attention should be sought.

• If you miss a dose of this medicine, take it as soon as you remember. However, avoid taking a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of fluids can help manage headaches and dry mouth.

• Rest and avoid strenuous activity if feeling dizzy or fatigued.

Use in Driving and Operating Machinery

• Metoclopramide + Paracetamol/Acetaminophen may cause drowsiness or dizziness. It is therefore advisable not to drive or operate heavy machinery until you know how the medicine affects you.

Use in Pregnancy and Lactation

• The use of Metoclopramide + Paracetamol/Acetaminophen during pregnancy or while breastfeeding should be discussed with your doctor, due to the potential risks involved.

Caution in Other Conditions

• Patients with liver or kidney issues should exercise caution when taking Metoclopramide + Paracetamol/Acetaminophen. These conditions can affect how well your body processes the medicine, and may require dosage adjustments or special tests during treatment.

Special Dietary and Lifestyle Recommendations

• Avoiding known personal triggers for migraines, such as certain foods or fragrances, can be beneficial.