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Metronidazole + Tetracycline

Uses of Metronidazole + Tetracycline

  • Metronidazole + Tetracycline is primarily used for managing bacterial infections and falls under the group of antibiotics.

  • Secondary uses of this combination involve its application in eradicating Helicobacter pylori bacteria, treating severe gum disease (periodontitis), and managing inflammatory skin conditions like rosacea.

Side effects of Metronidazole + Tetracycline

  • Nausea

  • Vomiting

  • Diarrhoea

  • Abdominal pain

  • Skin rash

How Metronidazole + Tetracycline works

  • Metronidazole + Tetracycline is an antibiotic combination.

  • Metronidazole penetrates bacterial cells and its metabolic products disrupt the DNA and inhibit nucleic acid synthesis. This inhibits the growth and replication of anaerobic bacteria and certain parasites, leading to their death.

  • Tetracycline, on the other hand, enters bacterial cells where it binds to the 30S ribosomal subunit. This prevents protein synthesis, stopping the growth and replication of a broad spectrum of bacteria.

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Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Metronidazole + Tetracycline is available for oral use (tablets and suspension).

Age and Dose Restrictions

  • This medication is meant for use by adults and children above the age of 8 years.

Contraindications

  • Metronidazole + Tetracycline is contraindicated in individuals with known hypersensitivity to either component of the formulation.

  • It is also contraindicated for individuals with liver or kidney disease.

Other Medications to Avoid

  • This combination may interact with anticoagulants (such as warfarin), immunosuppressants (like cyclosporine and tacrolimus), anticonvulsants (including phenytoin and carbamazepine), and other antibiotics (such as penicillins and cephalosporins).

Overdose and Missed Dose

  • An overdose of Metronidazole + Tetracycline may lead to severe nausea, vomiting, and neurological symptoms. In case of a suspected overdose, it is crucial to seek medical attention promptly.

  • If you miss a dose of Metronidazole + Tetracycline, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the forgotten one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea or abdominal discomfort, try taking your doses with or after meals.

  • If you are experiencing a metallic taste in your mouth, rinsing with a saltwater solution may help.

  • For oral thrush, maintaining good oral hygiene can be beneficial.

Use in Driving and Operating Machinery

  • Metronidazole + Tetracycline may cause dizziness or weakness. You should avoid driving or operating heavy machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Metronidazole + Tetracycline is generally not recommended during pregnancy or while breastfeeding. It is essential to consult a doctor before using this medicine if you are pregnant or planning to conceive.

Caution in Other Conditions

  • Patients with existing liver or kidney conditions should use Metronidazole + Tetracycline with caution.

  • It is advisable for individuals with neurological disorders to consult their doctor due to potential neurological side effects.

Special Dietary and Lifestyle Recommendations

  • Avoid alcohol consumption during treatment and for at least three days after completing therapy with Metronidazole + Tetracycline to prevent adverse reactions.

  • Limit exposure to sunlight and UV rays; wearing protective clothing and applying broad-spectrum sunscreen can help reduce the risk of photosensitivity reactions associated with tetracycline.

  • Maintain adequate hydration throughout the treatment period to help manage potential gastrointestinal side effects.

  • Engage in regular dental hygiene practices such as brushing and flossing to prevent the development of oral thrush, especially if using this medication for extended periods.

Frequently asked questions

Yes, some people can have an allergic reaction to Metronidazole + Tetracycline. Symptoms of an allergic reaction include rash, itching, swelling, severe dizziness, and trouble breathing. If you experience any of these symptoms, stop taking the medicine and consult your doctor immediately.

The half-life of Metronidazole is about 8 hours while Tetracycline's half-life is between 6 to 12 hours. This means that most of the medicine should be cleared from your system within 48 hours after your last dose. However, this can vary depending on your metabolism, overall health, age, and dosage.

Metronidazole + Tetracycline tablets may contain lactose. If you are lactose intolerant or have a similar condition, you should consult your doctor before using this medicine.

Yes, it can be used in elderly patients. However, as kidney function decreases with age, dosage might need to be adjusted accordingly. Always consult your doctor for the appropriate dosage.

No, Metronidazole + Tetracycline is not a painkiller. It is an antibiotic used to manage bacterial infections.

No direct link has been established between Metronidazole + Tetracycline and menstrual cycle changes. However, underlying conditions or stress related to illness can influence menstrual cycles. If you notice significant changes, consult your doctor.

Dizziness and weakness are common side effects of Metronidazole + Tetracycline, which could be interpreted as sleepiness. If you experience extreme sleepiness, consult your doctor.

Terms & Conditions


Available medicines for METRONIDAZOLE + TETRACYCLINE
Metrocline Capsule 10
Metrocline Capsule 10
Espee Formulation Pvt. Ltd.
Pack of 10 Units
₹26.98
MRP ₹32.90
18.00% OFF
Entakon M 400/333 MG Capsule 10
Entakon M 400/333 MG Capsule 10
Kontest Chemicals Ltd.
Pack of 10 Units
₹32.80
MRP ₹40.00
18.00% OFF
Meklin Capsule 10
Meklin Capsule 10
Bennet Pharmaceuticals Limited
Pack of 10 Units
₹47.81
MRP ₹58.30
18.00% OFF

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