Minocycline

Dosage Forms Available

• Minocycline is available in various dosage forms for administration via different routes. It can be consumed orally (capsules, tablets and oral suspension).

• It is also available in injection form and can be administered intravenously (IV) by a healthcare professional.

Age and Dose Restrictions

• Minocycline is prescribed for both adults and children; however, it should generally be avoided in children under 8 years of age, as it can cause permanent tooth staining. It may only be used in young children for specific conditions, such as inhalational anthrax, or when a doctor determines it is necessary.

Contraindications

• Minocycline is contraindicated in individuals who have shown hypersensitivity to tetracyclines in the past. This medication should be used with caution in patients with liver or kidney impairment, as dose adjustments may be necessary.

Other Medications to Avoid

• Minocycline may interact with antacids (such as aluminium hydroxide and magnesium carbonate), iron supplements (like ferrous sulphate), calcium supplements (like calcium carbonate), retinoids (such as isotretinoin) and anti-ulcer medicines (like cimetidine).

Overdose and Missed Dose

• Overdosing on Minocycline may lead to serious symptoms, including nausea, vomiting, and dizziness. If you suspect an overdose, you should seek immediate medical attention.

• If you miss a dose of Minocycline, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage gastrointestinal side effects like nausea, taking the medicine after meals might help.

• Sipping on water throughout the day can relieve dry mouth, which is another common side effect.

Use in Driving and Operating Machinery

• Minocycline may cause dizziness or drowsiness in some individuals. If you experience these symptoms, it is advisable to avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Minocycline can cause harm to the foetus when administered to a pregnant woman. It should only be used during pregnancy if the potential benefits outweigh the risks.

• As this medicine crosses into breast milk, alternate antibiotics are preferred during breastfeeding.

Caution in Other Conditions

• Patients with liver or kidney disease should exercise caution when taking Minocycline, as dose adjustments may be necessary. It should also be used with caution in patients with myasthenia gravis (a chronic autoimmune neuromuscular disease) as it may worsen muscle weakness.

Special Dietary and Lifestyle Recommendations

• Dairy products, antacids, and iron supplements should be avoided within two to three hours of taking a dose, as they can interfere with absorption.

• Sun exposure should be minimised during treatment with Minocycline as it may cause photosensitivity reactions. When going outdoors, wearing protective clothing and applying sunscreen with a high SPF can help prevent burns.