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Moxifloxacin + Tobramycin

Uses of Moxifloxacin + Tobramycin

  • Moxifloxacin + Tobramycin is primarily used for the management of bacterial infections of the eye, such as conjunctivitis and corneal ulcers. It belongs to the fluoroquinolone and aminoglycoside class of antibiotics.

  • Additionally, it may be used to prevent eye infections following ocular surgeries or injuries.

Side effects of Moxifloxacin + Tobramycin

  • Eye irritation

  • Burning sensation in the eye

  • Eye redness

  • Blurred vision

  • Headache

How Moxifloxacin + Tobramycin works

  • Moxifloxacin + Tobramycin is an antibiotic combination.

  • Moxifloxacin is a fluoroquinolone antibiotic that stops bacteria from multiplying by blocking DNA gyrase and topoisomerase IV enzymes, which are essential for bacterial DNA replication.

  • Tobramycin, an aminoglycoside antibiotic, binds to the 30S subunit of the bacterial ribosome, disrupting protein production and damaging the bacterial cell membrane, leading to bacterial death.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Moxifloxacin + Tobramycin is available in the form of eye drops or ointment.

Age and Dose Restrictions

  • Moxifloxacin + Tobramycin is suitable for use in both adults and children.

  • The safe age range depends on the condition and should be determined by a doctor.

Contraindications

  • This combination is contraindicated for patients with known hypersensitivity to either Moxifloxacin, Tobramycin or any other quinolone or aminoglycoside antibiotic.

  • Patients with viral or fungal eye infections should not receive this medication.

  • It should not be used in patients with myasthenia gravis, a history of tendon disorders, liver problems, or prolonged QT interval on an ECG.

Other Medications to Avoid

  • Moxifloxacin + Tobramycin may interact with antacids, sucralfate (protectant), multivitamins and didanosine (for instance Videx), warfarin (such as Coumadin), oral hypoglycemic medications (such as Metformin) and nephrotoxic or ototoxic medications like loop diuretics and platinum compounds (for example cisplatin).

  • Always consult your doctor before starting any prescription or over-the-counter medications.

Overdose and Missed Dose

  • An overdose of this medicine is unlikely with topical ophthalmic use. However, prolonged exposure may damage the corneal epithelium.

  • If you miss a dose of this medication, apply it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue as usual.

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage eye irritation, burning, stinging, or discomfort caused by this medication, try closing your eyes for a few minutes after application.

  • If you experience eye dryness, use a lubricating eye drop or artificial tear solution (available over the counter) to keep your eyes moist.

Use in Driving and Operating Machinery

  • This medicine may cause blurred vision.

  • If you experience this side effect, avoid driving or operating heavy machinery until your vision is clear.

Use in Pregnancy and Lactation

  • Moxifloxacin + Tobramycin is considered safe in pregnancy due to minimal systemic absorption.

  • Small amounts of this medication may pass into breast milk but are unlikely to harm the infant.

  • However, it is always advised to consult your doctor before using this medicine during pregnancy or breastfeeding.

Caution in Other Conditions

  • Patients with pre-existing renal, vestibular, or hearing impairment should exercise caution when using Moxifloxacin + Tobramycin.

Special Dietary and Lifestyle Recommendations

  • Maintain good eye hygiene to prevent further infection.

  • Avoid touching the tip of the eye dropper or ointment tube to prevent contamination.

  • Do not wear contact lenses when you have an eye infection.

  • Protect your eyes from dust, insects, and other potential sources of infection.

Frequently asked questions

No, you should complete the full course of Moxifloxacin + Tobramycin as prescribed by your doctor. Stopping early, even if symptoms improve, can lead to the infection returning or the bacteria becoming resistant to treatment.

No, Moxifloxacin + Tobramycin is effective only against bacterial eye infections. It has no activity against viruses.

Some people may experience temporary blurred vision after applying Moxifloxacin + Tobramycin. If this happens, avoid driving or operating machinery until your vision clears.

While tobramycin can affect the kidneys when used systematically, its ophthalmic use is generally safe even in people with kidney problems due to minimal systemic absorption.

No, it is not recommended to wear contact lenses while having an eye infection or during treatment with Moxifloxacin + Tobramycin.

Yes, but it should be administered under the supervision of a doctor and only if prescribed by them.

Moxifloxacin can make your eyes more sensitive to sunlight, so it is advisable to avoid exposure to strong sunlight or wear sunglasses during treatment.

Terms & Conditions


Available medicines for MOXIFLOXACIN + TOBRAMYCIN
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Moxitobra Eye Drops 5ml
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