Naproxen
Uses of Naproxen
The primary use of Naproxen is to manage pain and inflammation associated with various conditions. It belongs to the group of non-steroidal anti-inflammatory medicines (NSAIDs).
Secondary uses of Naproxen include the management of conditions such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, primary dysmenorrhea, tendinitis, bursitis and other forms of musculoskeletal pain. It is also used to provide relief from general pain, including headaches, migraines, toothaches and backaches.
Side effects of Naproxen
Stomach pain
Nausea
Diarrhoea
Headache
Dizziness
How Naproxen works
Naproxen is a Non-Steroidal Anti-Inflammatory Medicine (NSAID).
It primarily works by blocking a group of enzymes known as cyclooxygenases (COX-1 and COX-2). These enzymes are responsible for the production of chemical compounds called prostaglandins. Prostaglandins play a crucial role in our body's inflammation, pain, and fever responses. When Naproxen blocks these enzymes, it reduces the production of prostaglandins. As a result, it effectively manages inflammation, reduces pain, and lowers fever. Additionally, Naproxen may have some impact on blood clot formation by inhibiting the production of thromboxane A2 in the blood cells known as platelets. This contributes to its potential anti-thrombotic properties.
Certified content
Written By
Bachelor of Dental Surgery
Reviewed By
Doctor of Medicine
Expert Advice
Dosage Forms Available
Naproxen is available in several different oral forms (immediate-release tablets, enteric-coated tablets and oral suspension). It can also be taken rectally (suppositories) and topically (gel).
Age and Dose Restrictions
Naproxen is typically prescribed for adults.
Contraindications
Do not use this medication if you are allergic to it or any other non-steroidal anti-inflammatory medicines. This medication is also contraindicated for those who have a history of gastrointestinal problems such as ulcers, bleeding, or perforation.
Other Medications to Avoid
This medicine may interact with other NSAIDs and salicylates (such as ibuprofen and aspirin), anticoagulants and thrombolytics (like warfarin and streptokinase), ACE inhibitors (such as captopril and lisinopril) and diuretics (like furosemide and torsemide).
Overdose and Missed Dose
If you accidentally take too much Naproxen, you may experience symptoms such as nausea, vomiting, dizziness, drowsiness, black or bloody stools, or stomach pain. If you experience any of these symptoms after taking too much Naproxen, seek medical help immediately.
If you forget to take a dose of Naproxen, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you get a rash, itching, or bruising after taking Naproxen, stop taking the medication and seek medical help. These could be signs of an allergic reaction.
Use in Driving and Operating Machinery
Naproxen can sometimes cause side effects such as drowsiness or dizziness. If you do experience these side effects, you should avoid driving or operating heavy machinery until you feel fully alert again.
Use in Pregnancy and Lactation
Naproxen should only be used during pregnancy or breastfeeding if your doctor has advised that it is necessary. It is especially important to avoid taking Naproxen in the third trimester of pregnancy unless it is under strict medical supervision.
Caution in Other Conditions
If you have kidney or liver problems, you should use Naproxen with caution. Your doctor may adjust the normal dose or more frequent monitoring of your condition while you are taking this medication.
Special Dietary and Lifestyle Recommendations
Remember to stay well hydrated, especially during physical activity or in hot weather.
Frequently asked questions
Can I take Naproxen with paracetamol?
Yes, Naproxen can be taken with paracetamol for added pain relief as they work in different ways.
How long can I safely take Naproxen?
The duration of treatment with Naproxen will depend on the condition being treated. For acute conditions, you should use the lowest effective dose for the shortest possible time. For chronic conditions, long-term use should be under the supervision of a doctor.
Can I drink alcohol while taking Naproxen?
It is best to avoid drinking alcohol while taking Naproxen as it can increase the risk of gastrointestinal bleeding and other side effects.
Is Naproxen safe for children?
Naproxen is not generally recommended for children under 12 years old unless it is under the close supervision of a doctor.
Can Naproxen affect my mood?
Naproxen is not directly associated with affecting mood. However, pain and inflammation can affect your overall well-being and mood, so managing these symptoms with Naproxen may indirectly improve your mood.
Does Naproxen interact with certain foods?
There is no specific food that you need to avoid while taking Naproxen. However, taking it with food can help to reduce stomach upset.
Can Naproxen cause weight gain?
Naproxen is not directly associated with weight gain. However, if you notice significant changes in your weight while taking this medication, you should discuss this with your doctor.
Naproxen in other salts
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