Naproxen + Sumatriptan

Dosage Forms Available

• Naproxen + Sumatriptan is available in the form of tablets for oral administration. This combination is meant to be taken orally.

Age and Dose Restrictions

• This combination medicine is meant for use in adults. It is not recommended for use in children or adolescents under 18 years of age.

Contraindications

• Naproxen + Sumatriptan is contraindicated in patients with known hypersensitivity to either Naproxen or Sumatriptan.

• It should not be used in patients with a history of asthma, urticaria, or allergic reaction after taking aspirin or other NSAIDs.

• The combination is also contraindicated in patients who have recently had heart bypass surgery (CABG), severe liver impairment, active peptic ulcer disease, cerebrovascular or peripheral vascular disease, uncontrolled hypertension, and those who have been taking ergotamine medications or MAO inhibitors within the past 14 days.

Other Medications to Avoid

• Naproxen + Sumatriptan can interact with other NSAIDs (like ibuprofen and aspirin), anticoagulants (like warfarin and heparin), SSRIs and SNRIs (such as fluoxetine and duloxetine), lithium and MAO inhibitors, diuretics and ACE inhibitors, digoxin and methotrexate, and ergotamine and triptan medications.

Overdose and Missed Dose

• Overdose of Naproxen + Sumatriptan can intensify side effects like drowsiness, indigestion, flushing, hypertension and may also cause cardiac arrest, seizures or coma in extreme cases. In case of an overdose, seek immediate medical attention.

• If you forget to take Naproxen + Sumatriptan at the earliest sign of a migraine attack, take it as soon as you remember. However, do not double the dose to compensate for the missed one.

Management of Side Effects

Most side effects of Naproxen + Sumatriptan are temporary, generally harmless, and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

• Take the medication with food and stay hydrated to help minimize digestive side effects.

• After taking the medication, rest or lie down in a quiet, dim room to help manage symptoms like dizziness and vertigo.

Use in Driving and Operating Machinery

• Naproxen + Sumatriptan may cause dizziness, drowsiness or fatigue. Therefore, until you know how this medicine affects you, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Use of Naproxen + Sumatriptan during pregnancy should only be considered if the potential benefits to the mother outweigh the potential risks to the fetus.

• This combination is excreted in human milk. A decision should be made whether to discontinue nursing or discontinue the medicine after considering the importance of the medicine to the mother.

Caution in Other Conditions

• Patients with a history of ulcers or gastrointestinal (GI) bleeding, renal impairment, seizure disorders, or risk factors for heart disease should use Naproxen + Sumatriptan cautiously.

Special Dietary and Lifestyle Recommendations

• Maintain a regular sleeping schedule. Disrupted sleep-wake cycles can trigger migraines.

• Stay hydrated by drinking plenty of water throughout the day.

• Limit intake of caffeine as excessive consumption can lead to withdrawal headaches.

• Regular physical activity can help manage stress levels, which can be a trigger for migraines.

• Identify and avoid personal migraine triggers. These can be certain foods, smells, changes in weather, or even stress.

• Practice relaxation techniques like yoga, mindfulness, and meditation to manage stress and potentially decrease the frequency of migraines.

• Maintain a healthy balanced diet, avoiding foods that are known migraine triggers for you.