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Natamycin

Uses of Natamycin

  • Natamycin is used to manage fungal infections, particularly in the eye. It falls under the category of polyene antibiotics.

  • Aside from its medical uses, Natamycin is also employed as a food preservative. It helps prevent mould growth in certain dairy products like cheese.

Side effects of Natamycin

  • Eye irritation

  • Burning sensation

  • Stinging sensation

  • Temporary blurred vision

  • Rare allergic reactions like itching, swelling, or rash around the eyes

How Natamycin works

  • Natamycin is a naturally occurring antifungal agent.

  • It functions by binding to ergosterol, a primary component found in the cell membranes of fungi. This interaction disrupts the normal structure of the fungal cell membrane, causing leakage of vital cellular components and eventually leading to cell death. By selectively targeting ergosterol, a substance not present in human cells, Natamycin can prevent fungal growth without harming human tissues.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Natamycin is available as an ophthalmic suspension, which is instilled directly into the eye.

  • In the food industry, Natamycin is used in the form of a powder or solution for preservation purposes.

Age and Dose Restrictions

  • Natamycin is primarily prescribed for use in adults.

Contraindications

  • Natamycin is contraindicated in individuals with known hypersensitivity to this medicine or any of its components.

  • It is also contraindicated for patients with known allergies to polyene antibiotics.

Other Medications to Avoid

  • Natamycin may interact with other antifungal agents (e.g., amphotericin B and clotrimazole).

  • If other ophthalmic medications are being used concurrently with Natamycin, they should be administered at least 5 minutes apart to avoid dilution or washout of either medicine.

Overdose and Missed Dose

  • Overdosing on Natamycin is unlikely due to its low absorption rate. However, in case of accidental ingestion, patients should drink plenty of water and seek medical advice.

  • If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

  • If you experience eye irritation after applying Natamycin eye drops, rinsing the eye with water may help alleviate discomfort.

  • Patients experiencing temporary blurred vision after application should rest their eyes until their vision clears.

Use in Driving and Operating Machinery

  • Some patients may experience temporary blurred vision after applying Natamycin eye drops. As such, it is recommended to avoid driving or operating machinery until the vision clears.

Use in Pregnancy and Lactation

  • The safety of Natamycin during pregnancy and lactation has not been established. Pregnant or breastfeeding women should consult a doctor before using this medicine.

Caution in Other Conditions

  • No specific medical conditions have been identified for which caution needs to be taken while using Natamycin. However, as with any medicine, patients with chronic health conditions should consult their doctor before starting treatment.

Special Dietary and Lifestyle Recommendations

  • Individuals should maintain a high standard of eye hygiene to help manage fungal eye infections. This can include regularly washing hands before touching the eyes to prevent further infection.

  • Patients should avoid wearing contact lenses while using Natamycin for several days after stopping treatment to allow the eye to heal.

  • In the case of food preservation, manufacturers should ensure that their products are stored at appropriate temperatures to minimise mould growth and other microorganisms.

Frequently asked questions

No, Natamycin is not a steroid. It is a naturally occurring antifungal agent and belongs to the class of polyene antibiotics.

There is no information available suggesting that Natamycin has any direct effect on sleep.

Natamycin is usually available only with a doctor's prescription and is not typically sold over-the-counter.

The duration of treatment with Natamycin depends on the severity and type of infection being treated. Typically, treatment lasts for 2-3 weeks or until the infection resolves.

Yes, it is safe to take Natamycin daily as per your doctor's prescription and directions. Always adhere to the prescribed dosage and do not self-medicate.

Natamycin starts working immediately upon application, but visible improvement in symptoms may take several days. Most fungal eye infections require 2-3 weeks of treatment for complete resolution.

Natamycin should be taken as directed by your doctor. The timing could vary depending on the severity of the infection and the specific formulation used.

Terms & Conditions


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