Home/Drugs By Ailments / Nebivolol

Nebivolol

ANTIHYPERTENSIVE

Uses of Nebivolol

  • Nebivolol is used to manage hypertension (high blood pressure).
  • It inhibits elevated heart rate and regulates myocardial contractility. Additionally, it induces vasodilation in blood vessels, thereby aiding in the reduction of blood pressure.
  • It is also prescribed for the management of chronic heart failure in individuals aged 70 years or older, alongside other therapeutic interventions.

Side effects of Nebivolol

  • Diarrhoea
  • Constipation
  • Nausea
  • Shortness of breath
  • Swollen hands or feet
  • Headache
  • Dizziness
  • Tiredness
  • An unusual itching or tingling feeling

How Nebivolol works

Nebivolol functions as a β-adrenergic receptor blocking agent. In individuals with extensive metabolism (representing most of the population) and at doses equal to or less than 10 mg, nebivolol exhibits preferential selectivity for β1 receptors. In poor metabolisers and higher doses, nebivolol inhibits both β1- and β2-adrenergic receptors. Nebivolol does not possess intrinsic sympathomimetic or membrane-stabilizing activity at concentrations relevant to therapeutic effects. At clinically significant doses, Nebivolol does not display α1-adrenergic receptor blockade activity. Various metabolites, including glucuronides, contribute to the β-blocking activity.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Nebivolol is available for use via the oral route (tablet).

Age and Dose Restrictions

  • Nebivolol is meant for adults and children above 18 years of age.

Contraindications

  • Nebivolol is contraindicated in patients with known allergies to nebivolol, severe heart issues, bronchial asthma or related bronchospastic conditions, and diabetic ketoacidosis.

Other Medications To Avoid With This Medicine

  • The use of pain relievers (such as aspirin and ibuprofen), diuretics (including chlorthalidone, indapamide, furosemide, and hydrochlorothiazide), antihypertensives (like amlodipine and valsartan), PDE5 inhibitors (such as tadalafil and sildenafil), anxiety medications (including alprazolam and diazepam), and medications prescribed for heart problems (such as digoxin and epinephrine) is not recommended without prior consultation with your doctor. It is essential to consult with your doctor before using any prescription or over-the-counter medications.

Overdose and Missed Dose

  • Overdose of Nebivolol can cause a very slow heartbeat (bradycardia), low blood pressure with possible fainting, breathlessness such as asthma, and acute heart failure. Inform your doctor and follow the advice accordingly.
  • If you forget a Nebivolol dose, take it as soon as you remember. However, avoid repeating the dose.

Use In Driving And Operating Machinery

  • Nebivolol can affect your ability to drive or operate heavy machinery. 

Use in Pregnancy and Lactation

  • Nebivolol is not recommended during pregnancy or breastfeeding.

Caution In Other Conditions

  • Individuals diagnosed with hypertension and coronary artery disease are advised to implement lifestyle changes, including dietary adjustments such as following a low-sodium, low-carbohydrate, and low-fat diet. Furthermore, it is recommended to incorporate regular exercise, such as brisk walking for at least thirty minutes per day, five days a week, to manage blood pressure effectively.
  • Individuals dealing with hypertension continually face an ongoing risk of heart attacks and strokes. Consequently, it is essential to establish a routine for monitoring blood pressure, either by employing a digital blood pressure monitoring device at home or through regular visits to the doctor.

Special Dietary & Lifestyle Recommendation

  • Comprehensive education on recognising signs and symptoms associated with heart attacks and strokes is essential. This knowledge can enable timely interventions, minimising complications and promoting a quicker and more thorough recovery.

Frequently asked questions

It starts showing its effects within a few hours after consumption.

Avoid usage if you experience an allergic reaction (hypersensitivity) to Nebivolol. It is advisable to seek advice from a doctor promptly.

Do not stop taking this medication without consulting your doctor, even if you feel healthy.

 Consult your doctor before taking this medication if you have kidney or liver issues to ensure its safety and proper dosage.

This medication does not affect contraception.

Terms & Conditions


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