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Niacinamide

Uses of Niacinamide

  • The primary use of Niacinamide is for the prevention and treatment of pellagra, a disease caused by vitamin B3 deficiency. It belongs to the group of vitamin supplements.

  • Secondary uses of Niacinamide include managing various skin conditions, assisting in the management of diabetes, helping lower elevated blood phosphate levels in patients with kidney failure requiring haemodialysis, possible prevention of nonmelanoma skin cancers and precancerous lesions in high-risk individuals, and improving joint flexibility and reducing pain and inflammation in people with osteoarthritis.

Side effects of Niacinamide

  • Nausea

  • Vomiting

  • Diarrhoea

  • Headache

  • Dizziness

How Niacinamide works

  • Niacinamide is a form of vitamin B3.

  • It is involved in cellular energy production and metabolism because it converts into nicotinamide adenine dinucleotide (NAD) in the body. NAD acts as a coenzyme in many enzymatic reactions.

  • Niacinamide has distinct, anti-inflammatory effects that help reduce inflammation and regulate the skin's sebum production.

  • It can also improve the skin barrier function by increasing ceramide and free fatty acid levels, which are vital for maintaining healthy skin.

  • By inhibiting melanin production, Niacinamide contributes to its use in managing various skin conditions such as hyperpigmentation.

Certified content

Written By

docImg
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Niacinamide is available for use orally (tablet, capsule) and topical (cream) routes.

Age and Dose Restrictions

  • This medication is meant for adults and children above the age of 12 years.

  • The correct dosage varies based on the individual's condition and the doctor's advice.

Contraindications

  • Niacinamide is contraindicated in individuals with known hypersensitivity to any component of the formulation.

Other Medications to Avoid

  • Niacinamide may interact with anticoagulants (such as warfarin and aspirin), anticonvulsants (like carbamazepine and primidone), diabetes medications (such as metformin and insulin), isoniazid, and nicotine patches or gum.

Overdose and Missed Dose

  • An overdose of Niacinamide may cause symptoms such as nausea, vomiting, headache, dizziness, and fatigue. If you observe any of these symptoms, inform your doctor immediately.

  • If you miss a dose of Niacinamide, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For mild gastrointestinal issues like nausea or vomiting, it might help to take Niacinamide with food.

  • Staying hydrated can help manage potential side effects like dizziness or fatigue.

  • If topical Niacinamide causes mild irritation or redness, try applying it to a smaller area of the skin.

Use in Driving and Operating Machinery

  • Niacinamide does not usually affect your ability to drive or operate machinery. However, if you feel dizzy or unsteady after taking this medicine, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • Consult your doctor before using Niacinamide during pregnancy or breastfeeding. It should be used only if clearly necessary and under medical supervision.

Caution in Other Conditions

  • People with diabetes, gallbladder disease, gout, liver disorders, or peptic ulcers should use Niacinamide cautiously and under medical supervision.

  • Individuals with kidney failure requiring hemodialysis should also exercise caution when taking Niacinamide.

Special Dietary and Lifestyle Recommendations

  • Incorporate foods rich in vitamin B3 such as meat, fish, milk, eggs, green vegetables, and cereal grains into your diet.

  • Maintain a balanced diet to help manage blood sugar levels if you are using Niacinamide for diabetes.

  • Regular skin care routine including cleanliness and use of sunscreen can aid in managing skin conditions if using Niacinamide topically for skin issues.

Frequently asked questions

While Niacinamide plays a crucial role in many metabolic processes in the body, it is not directly associated with affecting mood enhancement.

No, there is no known connection between the intake of Niacinamide and alterations in appetite.

Yes, Niacinamide is naturally present in several foods including meat, fish, milk, eggs, green vegetables, and cereal grains.

Yes, you can use topical Niacinamide along with other skincare products. However, it is essential to consult your doctor or a skin care specialist before starting any new skincare regimen.

Yes, you can take Niacinamide every day. However, it should be used as per the recommended dietary allowance (RDA) or as directed by your doctor.

Niacinamide is not associated with affecting sleep disturbances. However, each individual's response to medication can be different, and if you notice any changes in your sleep pattern after taking Niacinamide, you should consult your doctor.

No, Niacinamide is not a steroid. It is a form of vitamin B3 that plays a vital role in cellular metabolism and maintaining healthy skin.

Terms & Conditions


Niacinamide in other salts

ASCORBIC ACID + BIOTIN + CALCIUM PANTOTHENATE + FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + RIBOFLAVIN + THIAMINE MONONITRATE + ZINC SULPHATEASCORBIC ACID + ELEMENTAL MANGANESE + ELEMENTAL SELENIUM + ELEMENTAL ZINC + FOLIC ACID + NIACINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + VITAMIN A + VITAMIN ERIBOFLAVIN + PYRIDOXINE + VITAMIN B12 + NIACINAMIDE + CALCIUM + FOLIC ACID + BIOTIN + ASCORBIC ACIDFOLIC ACID + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2BIOTIN + CALCIUM PANTOTHENATE + CYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACIDCYANOCOBALAMIN / VITAMIN B12 + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + FOLIC ACID + NIACINAMIDE + VITAMIN C / ASCORBIC ACIDFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN C / ASCORBIC ACIDD-PANTHENOL + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDEMETHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINED-PANTHENOL + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 (PYRIDOXINE)D-PANTHENOL + L-LYSINE + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINEBETA-CAROTENE + BIOTIN + CALCITRIOL/ CHOLECALCIFEROL + CHROMIUM + CYANOCOBALAMIN / VITAMIN B12 + INOSITOL + IODINE + LYSINE + MANGANESE + MOLYBDENUM + NIACINAMIDE + SELENIUM + VITAMIN B6 / PYRIDOXINE + ZINCCYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + L-LYSINE + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2 + THIAMINE / VITAMIN B1 + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN / VITAMIN B12 + L-LYSINE + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEFOLIC ACID + LACTIC ACID BACILLUS + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2
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